antibioticsАнтибиотики и ХимиотерапияAntibiot Khimioter = Antibiotics and Chemotherapy0235-2990ООО «Издательство ОКИ»10.37489/0235-2990-2024-69-3-4-62-72GNCNIGantibiotics-1127Research ArticleОБЗОРЫREVIEWSНанокапсулированные системы: перспективные биомедицинские инициативы в фармакологииNanoencapsulated Systems: Promising Biomedical Initiatives in Pharmacologyhttps://orcid.org/0000-0001-5417-4477ГенатуллинаГ. Н.GenatullinaG. N.

Генатуллина Гузель Наилевна — к. б. н., заместитель руководителя Научно-исследовательского центра; доцент кафедры фармакогнозии, фармацевтической технологии и биотехнологии

Астрахань

Guzel N. Genatullina — Ph. D. in Biology, Deputy Head of the Research Center; Associate Professor of the Department of Pharmacognosy, Pharmaceutical Technology, and Biotechnology

Astrakhan

https://orcid.org/0000-0003-2998-2864ЯсенявскаяА. Л.YasenyavskayaA. L.

Ясенявская Анна Леонидовна — к. м. н., доцент, руководитель Научно-исследовательского центра; доцент кафедры фармакогнозии, фармацевтической технологии и биотехнологии

Астрахань

Anna L. Yasenyavskaya — Ph. D. in Medicine, Associate Professor, Head of the Research Center; Associate Professor of the Department of Pharmacognosy, Pharmaceutical Technology, and Biotechnology

Astrakhan

yasen_9@mail.ruhttps://orcid.org/0000-0002-9994-4751ЦибизоваА. А.TsibizovaA. A.

Цибизова Александра Александровна — к. фарм. н., доцент кафедры фармакогнозии, фармацевтической технологии и биотехнологии

Астрахань

Alexandra A. Tsibizova — Ph. D. in Pharmaceutical Sciences, Associate Professor of the Department of Pharmacognosy, Pharmaceutical Technology, and Biotechnology

Astrakhan

https://orcid.org/0000-0001-5336-4455СамотруеваМ. А.SamotruevaM. A.

Самотруева Марина Александровна — д. м. н., профессор, заведующая кафедрой фармакогнозии, фармацевтической технологии и биотехнологии

Астрахань

Marina A. Samotrueva — D. Sc. in Medicine, Professor, Head of the Department of Pharmacognosy, Pharmaceutical Technology, and Biotechnology

Astrakhan

Астраханский государственный медицинский университетРоссияAstrakhan State Medical University of the Ministry of Health of the Russian FederationRussian Federation202421062024693-46272Copyright © ООО «Издательство ОКИ», 20242024ООО «Издательство ОКИ»ООО «Издательство ОКИ»https://www.antibiotics-chemotherapy.ru/jour/about/submissions#copyrightNoticehttps://www.antibiotics-chemotherapy.ru/jour/article/view/1127

Важнейшим направлением современной фармакологии является исследование систем, используемых для контролируемой и целенаправленной адресной доставки лекарственных препаратов, которое реализуется путём создания нанокапсулированных форм, имеющих различную природу и химическое строение. Нанокапсулирование — перспективный метод создания инновационных лекарственных форм с пролонгированным действием, позволяющий расширить номенклатуру лекарственных средств и изменить подходы к лечению различных заболеваний, требующих длительной терапии. В данном обзоре представлена информация, освещающая наиболее перспективные классы наноразмерных носителей лекарственных средств, описаны технологические процессы их получения на основе липидов, полимеров и биодеградируемых минеральных веществ, а также приведены примеры использования в современной фармацевтической практике.

The most important direction of modern pharmacology is the study of systems used for controlled and targeted delivery of medications, which is carried out by creating nanoencapsulated forms of different nature and chemical structure. Nanoencapsulation is a promising method for creating innovative dosage forms with prolonged action, which allows expanding the range of medications, as well as changing approaches to various diseases that require long-term therapy. This review provides information highlighting the most promising classes of nanosized drug carriers, describes the processes of their use based on lipids, polymers, and biodegradable mineral substances, as well as provides examples of their use in modern pharmaceutical practice.

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The authors declare that there are no conflicts of interest present.