antibioticsАнтибиотики и ХимиотерапияAntibiot Khimioter = Antibiotics and Chemotherapy0235-2990ООО «Издательство ОКИ»10.37489/0235-2990-2025-70-1-2-88-99PSCHFEantibiotics-1227Research ArticleОБЗОРЫREVIEWSАктуальный взгляд на лечение новой коронавирусной инфекции COVID-19Current Perspective on the Treatment of the Novel Coronavirus Infection COVID-19https://orcid.org/0000-0003-1180-228XБорукаеваИ. Х.BorukaevaI. Kh.

Ирина Хасанбиевна Борукаева, д. м. н., доцент, заведующая кафедрой

Медицинская академия; кафедра нормальной и патологической физиологии человека 

Нальчик

Irina Kh. Borukaeva, D. Sc. in Medicine, Associate Profes-sor, Head of the Department

Medical Academy; Department of Normal and PathologicalHuman Physiology

Nalchik

https://orcid.org/0000-0003-2827-5068АбазоваЗ. Х.AbazovaZ. Kh.

Залина Хасановна Абазова, к. м. н., доцент, доцент кафедры

Медицинская академия; кафедра нормальной и патологической физиологии человека

Нальчик

Zalina Kh. Abazova, Ph. D. in Medicine, Associate Professor; Associate Professor of the Department

Medical Academy; Department of Normal and Pathological Human Physiology

Nalchik

КамбачоковаЗ. А.KambachokovaZ. A.

Зарета Анатольевна Камбачокова, д. м. н., профессор

Медицинская академия; кафедра госпитальной терапии

Нальчик

Zareta A. Kambachokova, D. Sc. in Medicine, Professor

Medical Academy; Department of Hospital Therapy

Nalchik

k.zareta.7@mail.ruКамбачоковаА. А.KambachokovaA. A.

Амина Аслановна Камбачокова, студентка 4 курса поспециальности «Лечебное дело»

Медицинская академия

Нальчик

Amina A. Kambachokova, 4th year student with a GeneralMedicine major

Medical Academy

Nalchik

КардановА. А.KardanovA. A.

Азамат Алимович Карданов,  студент 4 курса по специальности «Лечебное дело»

Медицинская академия

Нальчик

Azamat A. Kardanov, 4th year student with a General Medi-cine major

Medical Academy

Nalchik

ДжабраиловаМ. С.DjabrailovaM. S.

Мислина Султановна Джабраилова, студентка 6 курсапо специальности «Лечебное дело»

Медицинская академия

Нальчик

Mislina S. Djabrailova, 6th year student with a GeneralMedicine major

Medical Academy

Nalchik

ЧаниеваЗ. И.СhanievaZ. I.

Зимфира Иссаевна Чаниева, студентка 6 курса по специальности «Лечебное дело»

Медицинская академия

Нальчик

Zimfira I. Сhanieva, 6th year student with a General Medicinemajor

Medical Academy

Nalchik

АхматовХ. Х.AkhmatovKh. Kh.

Халид Хасиевич Ахматов, студент 6 курса по специальности «Лечебное дело»

Медицинская академия

Нальчик

Khalid Kh. Akhmatov, 6th-year student with a General Med-icine major

Nalchik

АбдурахмановМ. А.AbdurakhmanovM. A.

Магомед Абдурахманович Абдурахманов, студент 6 курсапо специальности «Лечебное дело»

Медицинская академия

Нальчик

Magomed A. Abdurakhmanov, 6th year student with a General Medicine major

Medical Academy

Nalchik

БаскариевШ. М.BaskarievSh. M.

Шаабан Магомедович Баскариев, студент 6 курса поспециальности «Лечебное дело»

Медицинская академия

Нальчик

Shaaban M. Baskariev, 6th year student with a General Med-icine major

Medical Academy

Nalchik

МежгиховаЭ. Б.MezhikhovaE. B.

Элана Барасбиевна Межгихова, студентка 6 курса поспециальности «Педиатрия»

Медицинская академия

Нальчик

Elana B. Mezhikhova, 6th year student with a General Med-icine major

Medical Academy

Nalchik

ШогеноваД. А.ShogenovaD. A.

Диана Аслановна Шогенова, студентка 6 курса по специальности «Педиатрия»

Медицинская академия

Нальчик

Diana A. Shogenova, 6th year student with a General Medicine major

Medical Academy

Nalchik

ФГБОУ ВО «Кабардино-Балкарский государственный университет им. Х. М. Бербекова»РоссияKabardino-Balkarian State University named after H. M. BerbekovRussian Federation202509062025701-28899Copyright © Борукаева И.Х., Абазова З.Х., Камбачокова З.А., Камбачокова А.А., Карданов А.А., Джабраилова М.С., Чаниева З.И., Ахматов Х.Х., Абдурахманов М.А., Баскариев Ш.М., Межгихова Э.Б., Шогенова Д.А., 20252025Борукаева И.Х., Абазова З.Х., Камбачокова З.А., Камбачокова А.А., Карданов А.А., Джабраилова М.С., Чаниева З.И., Ахматов Х.Х., Абдурахманов М.А., Баскариев Ш.М., Межгихова Э.Б., Шогенова Д.А.Borukaeva I.K., Abazova Z.K., Kambachokova Z.A., Kambachokova A.A., Kardanov A.A., Djabrailova M.S., Сhanieva Z.I., Akhmatov K.K., Abdurakhmanov M.A., Baskariev S.M., Mezhikhova E.B., Shogenova D.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.antibiotics-chemotherapy.ru/jour/article/view/1227

   COVID-19, вызванный новым коронавирусом SARS-CoV-2, стал одной из самых серьёзных глобальных проблем здравоохранения за последние десятилетия. Лечение этого заболевания оказалось сложной задачей из-за отсутствия специфического лечения и чёткого понимания его патогенеза. Проведённый анализ литературы по лечению новой коронавирусной инфекции COVID-19 в различные периоды показал, что назначение многих препаратов было стихийным, без доказательной базы, основываясь на предположительных эффектах, что объяснялось необходимостью быстрого реагирования со стороны медицинского сообщества. Однако безопасность многих препаратов оставалась недостаточно изученной. Кроме того, при применении различных групп препаратов, от противовирусных средств до кортикостероидов, важно было учитывать взаимодействие между различными препаратами для минимизации рисков для пациентов. В статье освещены результаты ретроспективного исследования эффективности и побочных эффектов основных групп препаратов, применяемых при лечении COVID-19.

   COVID-19, caused by the novel coronavirus SARS-CoV-2, has emerged as one of the most serious global health challenges in recent decades. The treatment of this condition has proven to be a complex task due to the lack of specific therapies and a clear understanding of its pathogenesis. A review of the literature on the treatment of COVID-19 at various stages has indicated that the prescription of many medications was often spontaneous and lacked an evidence-based foundation, relying instead on presumed effects. This approach was largely driven by the necessity for rapid response from the medical community. However, the safety of many of these medications remains inadequately studied. Furthermore, when employing various groups of medications — ranging from antiviral agents to corticosteroids — it is crucial to consider potential interactions among different drugs to minimize risks for patients. This article presents the results of a retrospective study on the efficacy and side effects of the main groups of medications used in the treatment of COVID-19.

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The authors declare that there are no conflicts of interest present.