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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">antibiotics</journal-id><journal-title-group><journal-title xml:lang="ru">Антибиотики и Химиотерапия</journal-title><trans-title-group xml:lang="en"><trans-title>Antibiot Khimioter = Antibiotics and Chemotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0235-2990</issn><publisher><publisher-name>ООО «Издательство ОКИ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37489/0235-2990-2025-70-1-2-113-123</article-id><article-id custom-type="edn" pub-id-type="custom">ZDBXUZ</article-id><article-id custom-type="elpub" pub-id-type="custom">antibiotics-1229</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Нейропсихофармакологические аспекты действия антибиотиков</article-title><trans-title-group xml:lang="en"><trans-title>Neuropsychopharmacological Aspects of Antibiotic Action</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6183-2586</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергеев</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergeev</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юрий Андреевич Сергеев, к. м. н., старший преподаватель</p><p>кафедра фармакологии</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Yuri A. Sergeev, Ph. D. in Medicine, senior lecturer</p><p>Department of Pharmacology</p><p>Stavropol</p></bio><email xlink:type="simple">serg_yuriy@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3248-6212</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бейер</surname><given-names>Э. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Beyer</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Эдуард Владимирович Бейер, д. м. н., доцент, заведующий кафедрой</p><p>кафедра фармакологии</p><p>Ставрополь</p></bio><bio xml:lang="en"><p>Eduard V. Beyer, D. Sc. in Medicine, Associate Professor, Head of the Department</p><p>Department of Pharmacology</p><p>Stavropol</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ставропольский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>09</day><month>06</month><year>2025</year></pub-date><volume>70</volume><issue>1-2</issue><fpage>113</fpage><lpage>123</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сергеев Ю.А., Бейер Э.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Сергеев Ю.А., Бейер Э.В.</copyright-holder><copyright-holder xml:lang="en">Sergeev Y.A., Beyer E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.antibiotics-chemotherapy.ru/jour/article/view/1229">https://www.antibiotics-chemotherapy.ru/jour/article/view/1229</self-uri><abstract><p>   В обзоре обобщены современные данные экспериментальных и клинических исследований о свойствах антибиотиков с точки зрения нейропсихофармакологии. На фоне выраженной антибиотикорезистентности потенциальный интерес представляют сторонние эффекты такого рода препаратов, интересным в таком случае является возможность последних оказывать влияние на психические функции, когнитивный статус, ноцицептивную систему, а также их участие в развитии нарушений сна.</p></abstract><trans-abstract xml:lang="en"><p>   The review summarizes current data from experimental and clinical studies on the properties of antibiotics from the point of view of neuropsychopharmacology. Against the background of pronounced antibiotic resistance, the side effects of such drugs are of potential interest. Therefore, the possibility of the latter influencing mental functions, cognitive status, nociceptive system, as well as their involvement in the development of sleep disorders, are of particular interest.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>антибиотики</kwd><kwd>нейропсихофармакология</kwd><kwd>психофармакологические свойства антибиотиков</kwd><kwd>побочные эффекты антибиотиков</kwd></kwd-group><kwd-group xml:lang="en"><kwd>antibiotics</kwd><kwd>neuropsychopharmacology</kwd><kwd>psychopharmacological properties of antibiotics</kwd><kwd>side effects of antibiotics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Althubyani A. A., Canto S., Pham H., Holger D. J., Rey J. Antibiotic-induced neuropsychiatric toxicity: epidemiology, mechanisms and management strategies — a narrative literature review. Drugs Context. 2024; 13: 2024-3-3. 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