antibioticsАнтибиотики и ХимиотерапияAntibiot Khimioter = Antibiotics and Chemotherapy0235-2990ООО «Издательство ОКИ»10.37489/0235-2990-2025-70-7-8-92-100XIGQOYantibiotics-1274Research ArticleОБЗОРЫREVIEWSК вопросу об антибактериальной терапии болезни ЛаймаOn The Issue of Antibiotic Therapy for Lyme Diseasehttps://orcid.org/0000-0001-7091-2054БеловБ. С.BelovB. S.

Белов Борис Сергеевич — д. м. н., заведующий лабораторией коморбидных инфекций и вакцинопрофилактики, ResearcherID: ABD-2219-2020. eLIBRARY SPIN-код: 3298-4315. Scopus Author ID: 7004592537.

Москва

Boris S. Belov — D. Sc. in Medicine, Head of the Laboratory of Comorbid Infections and Vaccine Prevention, ResearcherID: ABD-2219-2020. eLIBRARY SPIN-code: 3298-4315. Scopus Author ID: 7004592537.

Moscow

belovbor@yandex.ruhttps://orcid.org/0000-0002-3248-6426АнаньеваЛ. П.AnanyevaL. P.

Ананьева Лидия Петровна — д. м. н., профессор, научный консультант лаборатории системного склероза, ResearcherID: U-7411-2017. eLIBRARY SPIN-код: 7182-3868. Scopus Author ID: 6603356433

Москва

Lidia P. Ananyeva — D. Sc. in Medicine, Professor, Scientific Consultant at the Laboratory of Systemic Sclerosis. ResearcherID: U-7411-2017. eLIBRARY SPIN-code: 7182-3868. Scopus Author ID: 7004592537.

Moscow

ФБГНУ НИИ ревматологии им. В.А. НасоновойРоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation202511112025707-892100Copyright © Белов Б.С., Ананьева Л.П., 20252025Белов Б.С., Ананьева Л.П.Belov B.S., Ananyeva L.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.antibiotics-chemotherapy.ru/jour/article/view/1274

Болезнь Лайма (БЛ) или клещевой боррелиоз ежегодно поражает тысячи людей в разных регионах мира, в первую очередь, США и Европы. При этом всё большую актуальность приобретают вопросы рациональной антимикробной терапии БЛ, направленной на достижение необходимого эффекта при минимизации токсичности и нежелательных явлений. В настоящем обзоре проанализированы данные литературы в отношении возможности проведения коротких курсов антибактериальной терапии БЛ. Актуальность рассматриваемой проблемы обусловливает необходимость проведения дальнейших исследований, направленных на оценку продолжительности лечения, с достаточными размерами выборки и чётко определёнными результатами терапии.

Lyme disease (LD), or tick-borne borreliosis, annually affects thousands of people in different parts of the world, primarily the United States and Europe. At the same time, the issues of rational antimicrobial therapy of LD, which is aimed at achieving the desired effect while minimizing toxicity and adverse events, are becoming increasingly relevant. This review analyzes the literature data on the possibility of conducting short courses of antibiotic therapy for LD. The urgency of the problem under consideration necessitates further studies aimed at assessing treatment duration, with sufficient sample sizes and clearly defined treatment outcomes.

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The authors declare that there are no conflicts of interest present.