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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">antibiotics</journal-id><journal-title-group><journal-title xml:lang="ru">Антибиотики и Химиотерапия</journal-title><trans-title-group xml:lang="en"><trans-title>Antibiot Khimioter = Antibiotics and Chemotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0235-2990</issn><publisher><publisher-name>ООО «Издательство ОКИ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">antibiotics-130</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Полисахариды морских водорослей в коррекции нарушений, связанных с метаболическим синдромом</article-title><trans-title-group xml:lang="en"><trans-title>Polysaccharides of Marine Algae in the Correction of Disorders Associated with Metabolic Syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беседнова</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Besednova</surname><given-names>N. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крыжановский</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kryzhanovskiy</surname><given-names>S. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Звягинцева</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvyagintseva</surname><given-names>T. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Персиянова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Persiyanova</surname><given-names>YE. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корнеева</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korneeva</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт эпидемиологии и микробиологии им. Г. П. Сомова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Somov Institute of Epidemiology and Microbiology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Дальневосточный Федеральный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Far Eastern Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Тихоокеанский институт биоорганической химии им. Г. Б. Елякова ДВО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>G. B. Elyakov Pacific Institute of Bioorganic Chemistry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Медицинское объединение Дальневосточного отделения Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Association of the Far Eastern Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>06</day><month>05</month><year>2020</year></pub-date><volume>64</volume><issue>3-4</issue><fpage>59</fpage><lpage>70</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Беседнова Н.Н., Крыжановский С.П., Звягинцева Т.Н., Персиянова Е.В., Корнеева И.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Беседнова Н.Н., Крыжановский С.П., Звягинцева Т.Н., Персиянова Е.В., Корнеева И.А.</copyright-holder><copyright-holder xml:lang="en">Besednova N.N., Kryzhanovskiy S.P., Zvyagintseva T.N., Persiyanova Y.V., Korneeva I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.antibiotics-chemotherapy.ru/jour/article/view/130">https://www.antibiotics-chemotherapy.ru/jour/article/view/130</self-uri><abstract><p>В настоящем обзоре представлена информация о влиянии сульфатированных полисахаридов (СПС) из морских водорослей на компоненты метаболического синдрома (ожирение, липидный обмен, диабет 2-го типа, гипертоническая болезнь) и возможности коррекции нарушений, обусловленных с этим состоянием, а также с социально-значимыми заболеваниями, связанными с ним. Исследований эффективности этих соединений, проведённых в клинических условиях, мало, хотя по фармакологическому действию (антидислипидемическому, иммуномодулирующему, противовоспалительному, сахароснижающему и пр.) они сопоставимы с лекарственными препаратами (в частности, со статинами), а по безопасности для здоровья, как правило, превосходят их. Авторы обращают внимание на то, что СПС из морских водорослей могут быть основой для создания лекарственных препаратов, БАД к пище, а также продуктов функционального питания для пациентов с метаболическим синдромом.</p></abstract><trans-abstract xml:lang="en"><p>This review provides information on the effects of sulfated polysaccharides (SPS) derived from algae on the components of the metabolic syndrome (obesity, lipid metabolism, type 2 diabetes, hypertension) and the possibility of correcting disorders associated with this condition, as well as socially significant diseases associated with it. There are few studies of the effectiveness of these compounds conducted in a clinical setting, although in terms of their pharmacological action (antidyslipidemic, immunomodulatory, anti-inflammatory, hypoglycemic, etc.) they are comparable with medications (with statins, in particular), as for health safety, they are most commonly superior to those medications. The authors draw attention to the fact that seaweed-derived SPS can be the basis for the creation of medications, dietary supplements, as well as functional foods for patients with metabolic syndrome.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>метаболический синдром</kwd><kwd>коррекция</kwd><kwd>полисахариды морских водорослей</kwd><kwd>сахарный диабет</kwd><kwd>гипертоническая болезнь</kwd><kwd>дислипидемия</kwd><kwd>ожирение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>metabolic syndrome</kwd><kwd>correction</kwd><kwd>algae polysaccharides</kwd><kwd>diabetes mellitus</kwd><kwd>hypertension</kwd><kwd>dyslipidemia</kwd><kwd>obesity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
