antibioticsАнтибиотики и ХимиотерапияAntibiot Khimioter = Antibiotics and Chemotherapy0235-2990ООО «Издательство ОКИ»10.37489/0235-2990-2025-70-11-12-92-99QUMUEKantibiotics-1315Research ArticleОБЗОРЫREVIEWSПищевые источники гормонов и их воздействие на физиологическое состояние человека: аналитический обзорDietary Sources of Hormones and Their Impact on Human Physiological State: An Analytical Reviewhttps://orcid.org/0000-0003-1948-1687ХашироваС. С.KhashirovaS. S.

Хаширова Седа Сайпудиновна — м. н. с., НИЛ ЭК.

Нальчик

Seda S. Khashirova — Junior Researcher, Kabardino-Balkarian State University named after H.M. Berbekov.

Nalchik

seda.aslakhanova@gmail.comhttps://orcid.org/0000-0001-5898-2412ЛамашвилиЛ. С.LamashviliL. S.

Ламашвили Людмила Сайрамбаевна — н. с., зав. лаборатории НИЛ ЭК ФГБОУ ВО КБГУ, им. Х.М. Бербекова; ФГБУ Кабардино-Балкарский Государственный Высокогорный заповедник.

Нальчик

Lyudmila S. Lamashvili — Researcher, Head of the Research Laboratory of Ecology, Kabardino-Balkarian State University named after H.M. Berbekov, Federal State Budgetary Institution Kabardino-Balkarian State High-Mountain Nature Reserve.

Nalchik

https://orcid.org/0009-0000-3832-034XАгоеваЭ. А.AgoevaE. A.

Агоева Элеонора Анатольевна — аспирант, с. н. с., НИЛ ЭК ФГБОУ ВО КБГУ, им. Х.М. Бербекова; ФГБУ Кабардино-Балкарский Государственный Высокогорный заповедник.

Нальчик

Eleonora A. Agoeva — postgraduate student, Senior Researcher, Kabardino-Balkarian State University named after H.M. Berbekov, Federal State Budgetary Institution Kabardino-Balkarian State High-Mountain Nature Reserve.

Nalchik

https://orcid.org/0000-0001-9949-5709СнетковП. П.SnetkovP. P.

Снетков Пётр Петрович — к. т. н., ФГБОУ ВО КБГУ им. Х М. Бербекова.

Нальчик

Petr P. Snetkov — Ph. D. in Engineering, Kabardino-Balkarian State University named after Kh.M. Berbekov.

Nalchik

https://orcid.org/0000-0002-7210-1252ХашироваС. Ю.KhashirovaS. Yu.

Хаширова Светлана Юрьевна — д. х. н., профессор, член-корреспондент РАН, проректор по НИР, ФГБОУ ВО КБГУ им. Х.М. Бербекова.

Нальчик

Svetlana Yu. Khashirova — D. Sc. in Chemistry, Professor, Corresponding Member of the Russian Academy of Sciences, Vice-Rector for Research, Kabardino-Balkarian State University named after H.M. Berbekov.

Nalchik

ФГБОУ ВО Кабардино-Балкарский Государственный университет, им. Х.М. БербековаРоссияKabardino-Balkarian State University named after Kh.M. BerbekovRussian FederationФГБОУ ВО Кабардино-Балкарский Государственный университет, им. Х.М. Бербекова; ФГБУ Кабардино-Балкарский Государственный Высокогорный заповедникРоссияKabardino-Balkarian State University named after Kh.M. Berbekov; Kabardino-Balkarian State High-Mountain Nature ReserveRussian FederationФГБОУ ВО Кабардино-Балкарский Государственный университет, им. Х.М. БербековаРоссияKabardino-Balkarian State University named after Kh. M. BerbekovRussian Federation2025040320267011-129299Copyright © ООО «Издательство ОКИ», 20262026ООО «Издательство ОКИ»ООО «Издательство ОКИ»https://www.antibiotics-chemotherapy.ru/jour/about/submissions#copyrightNoticehttps://www.antibiotics-chemotherapy.ru/jour/article/view/1315

Экзогенные и эндогенные гормоны встречаются во многих продуктах питания — от стероидных имплантатов и рекомбинантных факторов роста, используемых в животноводстве и молочном производстве, до природных гормонов, присутствующих в продуктах животного происхождения. В связи с растущим числом эндокринных и репродуктивных заболеваний, был проведён анализ современных данных о том, как пищевые гормоны влияют на физиологию и здоровье человека. К таким веществам относятся синтетические стимуляторы роста, стероиды животного происхождения и фитоэстрогены растений, которые могут попадать в рацион человека через мясные, молочные и соевые продукты. Были рассмотрены механизмы действия гормональных веществ на организм человека, а также данные об эндокринных и репродуктивных нарушениях, риске рака. Эпидемиологические и экспериментальные исследования обнаружили взаимосвязь между потреблением пищевых гормонов и эндокринными нарушениями, изменением сроков полового созревания и фертильности, метаболическими дисфункциями и гормонозависимыми видами рака. Сложность данной темы заключается в том, что нет единого мнения о взаимосвязи потребления гормонсодержащих продуктов и развитием перечисленных заболеваний, таким образом, подходы к регулированию потребляемых доз в разных странах различаются. В связи с этим в настоящем исследовании представлен обзор мировых нормативных значений содержания гормонов в продуктах, рассматриваются разновидность и происхождение данных соединений, обобщаются данные о их влиянии на здоровье человека и животных, а также обсуждаются риски и перспективы долговременного потребления эндокринных разрушителей.

Exogenous and endogenous hormones are found in many foods — from steroid implants and recombinant growth factors used in livestock and dairy production to natural hormones present in animal products. Due to the growing incidence of endocrine and reproductive diseases, an analysis of current data on the way dietary hormones affect human physiology and health was conducted. These substances include synthetic growth promoters, animal steroids, and plant phytoestrogens, which can enter the human diet through the consumption of meat, dairy, and soy products. The mechanisms of action of hormonal substances on the human body were examined, as well as data on endocrine disruption, cancer risk, and reproductive outcomes. Epidemiological and experimental studies have found associations between dietary hormone consumption and endocrine disruption, changes in the timing of puberty and fertility, metabolic dysfunctions, and hormone-dependent cancers. The complexity of this topic lies in the lack of consensus on the relationship between the consumption of hormone-containing products and the development of these diseases, resulting in varying approaches to regulating intake levels across countries. Therefore, this review provides an overview of global regulatory limits for hormone content in foods, examines the types and origins of these compounds, summarizes data on their impact on human and animal health, as well as discusses the risks and prospects of long-term consumption of endocrine disruptors.

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The authors declare that there are no conflicts of interest present.