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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">antibiotics</journal-id><journal-title-group><journal-title xml:lang="ru">Антибиотики и Химиотерапия</journal-title><trans-title-group xml:lang="en"><trans-title>Antibiot Khimioter = Antibiotics and Chemotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0235-2990</issn><publisher><publisher-name>ООО «Издательство ОКИ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">antibiotics-283</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GUIDELINES FOR PRACTITIONERS</subject></subj-group></article-categories><title-group><article-title>Динамика распространения резистентности к беталактамным антибиотикам среди Streptococcus pneumoniae и её клиническая значимость</article-title><trans-title-group xml:lang="en"><trans-title>Dynamics of Beta-Lactams Resistance Distribution in Streptococcus pneumoniae and Its Clinical Significance</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савинова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Savinova</surname><given-names>T. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сидоренко</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sidorenko</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буданов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Budanov</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грудинина</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Grudinina</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальное агентство клинической фармакологии и фармации, Москва; НИИ детских инфекций, Санкт-Петербург; Научный центр экспертизы средств медицинского применения, Москва; Государственный научный центр по антибиотикам, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Agency of Clinical Pharmacology Pharmacy, Moscow; Research Institute of Children Infections, St.Petersburg; Scientific Centre of Investigation of Medicinal Products, Moscow; National Research Centre of Antibiotics, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>13</day><month>05</month><year>2020</year></pub-date><volume>55</volume><issue>1-2</issue><fpage>12</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Савинова Т.А., Сидоренко С.В., Буданов С.В., Грудинина С.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Савинова Т.А., Сидоренко С.В., Буданов С.В., Грудинина С.А.</copyright-holder><copyright-holder xml:lang="en">Savinova T.A., Sidorenko S.V., Budanov S.V., Grudinina S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.antibiotics-chemotherapy.ru/jour/article/view/283">https://www.antibiotics-chemotherapy.ru/jour/article/view/283</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Austrian R. 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