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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">antibiotics</journal-id><journal-title-group><journal-title xml:lang="ru">Антибиотики и Химиотерапия</journal-title><trans-title-group xml:lang="en"><trans-title>Antibiot Khimioter = Antibiotics and Chemotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0235-2990</issn><publisher><publisher-name>ООО «Издательство ОКИ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">antibiotics-517</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GUIDELINES FOR PRACTITIONERS</subject></subj-group></article-categories><title-group><article-title>Алгоритм идентификации атипичныгх форм стафилококков (SSCVs) - возбудителей хронических гнойно-воспалительных процессов у людей</article-title><trans-title-group xml:lang="en"><trans-title>Algorithm of Identification of Atypical Variants of Staphylococci, Pathogens of Chronic Pyoinflammatory Processes in Humans</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чуркина</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Churkina</surname><given-names>L. N.</given-names></name></name-alternatives><email xlink:type="simple">Churkina@imv.kiev.ua</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бидненко</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Bidnenko</surname><given-names>S. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ванечутте</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vaneechoutte</surname><given-names>M. ..</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеева</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeeva</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макушенко</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Makushenko</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лютко</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Lutko</surname><given-names>O. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Озерянская</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Oserjanskaja</surname><given-names>N. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перунова</surname><given-names>Н. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Perunova</surname><given-names>N. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт микробиологии и вирусологии НАН Украины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Microbiology and Virology, National Academy of Sciences of the Ukraine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт ортопедии и травматологии АМН Украины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Traumatology and Orthopedics, Medical Academy of Sciences of the Ukraine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Гентский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Gent University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Институт эпидемиологии и инфекционных болезней АМН Украины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Epidemiology and Infectious Diseases, Medical Academy of Sciences of the Ukraine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Институт клеточного и внутриклеточного симбиоза УрО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Cellular and Intracellular Symbiosis, Urals Branch of Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>13</day><month>05</month><year>2020</year></pub-date><volume>58</volume><issue>11-12</issue><fpage>26</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чуркина Л.Н., Бидненко С.И., Ванечутте М..., Авдеева Л.В., Макушенко А.С., Лютко О.Б., Озерянская Н.М., Перунова Н.Б., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Чуркина Л.Н., Бидненко С.И., Ванечутте М., Авдеева Л.В., Макушенко А.С., Лютко О.Б., Озерянская Н.М., Перунова Н.Б.</copyright-holder><copyright-holder xml:lang="en">Churkina L.N., Bidnenko S.I., Vaneechoutte M..., Avdeeva L.V., Makushenko A.S., Lutko O.B., Oserjanskaja N.M., Perunova N.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.antibiotics-chemotherapy.ru/jour/article/view/517">https://www.antibiotics-chemotherapy.ru/jour/article/view/517</self-uri><abstract><p>Стафилококки - возбудители таких хронических рецидивирующих инфекций, как кистозный фиброз лёгких и остеомиелит, характеризуются атипичной морфологией колоний (атипичные формы стафилококков) и представляют собой субпопуляцию в клинически важных стафилококках. В связи с утратой в процессе мутаций ряда важных для рода Staphylococcus фенотипических характеристик идентификация этих вариантов стафилококков усложнена, а иногда невозможна. Разработан алгоритм идентификации атипичных форм SCVs S.aureus, показаны преимущества молекулярных методов, в частности tRNA - PCR анализа, а также использования диагностического препарата Диастаф для корректной идентификации атипичных форм стафилококков.</p></abstract><trans-abstract xml:lang="en"><p>Staphylococcal pathogens of chronic relapsing infections, such as cystic pneumosclerosis and osteomyelitis are characterized by atypical morphology of the colonies (atypical variants of staphylococci) and present a subpopulation in clinically significant staphylococci. Since the loss of some phenotypic characteristics important for the genus Staphylococcus due to mutations, identification of such staphylococcal variants is difficult and sometimes impossible. An algorithm of identification of atypical variants of S.aureus (SSCVs) was developed. The advantages of the molecular methods and in particular the tRNA-PCR analysis, as well as the use of the diagnostic preparation Diastaph for correct identification of Staphylococcus atypical variants were shown.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>атипичные формы стафилококков (SSCVs)</kwd><kwd>идентификация</kwd><kwd>Диастаф</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atypical variants of staphylococci (SSCVs)</kwd><kwd>identification</kwd><kwd>algorithm</kwd><kwd>Diastaph</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wei H.H., Wu K.G., Sy L.B., Chen C.J., Tang R.B. Infectious endocarditis in pediatric patients: analysis of 19 cases presenting at a medical center. 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