antibioticsАнтибиотики и ХимиотерапияAntibiot Khimioter = Antibiotics and Chemotherapy0235-2990ООО «Издательство ОКИ»antibiotics-612Research ArticleОБЗОРЫREVIEWSВторичные метаболиты морских микроорганизмов. I. Вторичные метаболиты морских актиномицетовSecondary Metabolites from Marine Microorganisms. I. Secondary Metabolites from Marine ActinomycetesОрловаТ. И.OrlovaT. I.noemail@neicon.ruБулгаковаВ. Г.BulgakovaV. G.noemail@neicon.ruПолинА. Н.PolinA. N.noemail@neicon.ruМосковский государственный университет им. М.В. ЛомоносоваРоссияM.V. Lomonosov Moscow State UniversityRussian Federation201513052020607-84759Copyright © ООО «Издательство ОКИ», 20202020ООО «Издательство ОКИ»ООО «Издательство ОКИ»https://www.antibiotics-chemotherapy.ru/jour/about/submissions#copyrightNoticehttps://www.antibiotics-chemotherapy.ru/jour/article/view/612

В обзоре представлены опубликованные в период с 2007 по 2014 гг. данные по вторичным метаболитам, синтезируемым определённой группой морских микроорганизмов - морскими актиномицетами. По химической структуре описанные метаболиты относятся к разным классам соединений и проявляют различную биологическую активность. Ряд метаболитов обладает антибиотическим действием в отношении бактерий, в том числе устойчивых патогенов, а также вирусов и грибов. Многие морские актиномицеты являются продуцентами цитотоксических соединений, проявляющих противораковую активность, а также синтезируют вещества - ингибиторы различных групп ферментов.

Review represents data on new active metabolites isolated from marine actinomycetes published in 2007 to 2014. Marine actinomycetes are an unlimited source of novel secondary metabolites with various biological activities.Among them there are antibiotics, anticancer compounds, inhibitors of biochemical processes.

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The authors declare that there are no conflicts of interest present.