antibioticsАнтибиотики и ХимиотерапияAntibiot Khimioter = Antibiotics and Chemotherapy0235-2990ООО «Издательство ОКИ»antibiotics-68Research ArticleОБЗОРЫREVIEWSПерспективные стратегии поиска новых средств борьбы с инфекционными заболеваниямиPerspective Strategies for Finding New Means of Fighting with Infectious DiseasesАндрюковБ. Г.AndryukovB. G.andrukov_bg@mail.ruЗапорожецТ. С.ZaporozhetsT. S.noemail@neicon.ruБеседноваН. Н.BesednovaN. N.noemail@neicon.ruНИИ эпидемиологии и микробиологии им. Г. П. СомоваРоссияG. P. Somov Research Institute of Epidemiology and MicrobiologyRussian Federation201806052020631-24455Copyright © Андрюков Б.Г., Запорожец Т.С., Беседнова Н.Н., 20202020Андрюков Б.Г., Запорожец Т.С., Беседнова Н.Н.Andryukov B.G., Zaporozhets T.S., Besednova N.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.antibiotics-chemotherapy.ru/jour/article/view/68

Возрастающая резистентность микроорганизмов к антибиотикам в последнее время перестаёт быть исключительно медицинской проблемой. Она затрагивает всё более широкий круг социально-экономических аспектов мирового сообщества и, достигнув высокого уровня, перерастает в глобальную угрозу здоровью населения планеты. В процессе эволюции бактерии выработали ряд эффективных стратегий защиты от антимикробных препаратов. Это обуславливает первостепенное значение разработки перспективных стратегий поиска альтернативных стратегий борьбы с инфекционными заболеваниями. В обзоре авторы обсуждают и анализируют несколько направлений поиска новых средств, потенциально способных стать альтернативой традиционной антибиотикотерапии.

Increasing resistance of microorganisms to antibiotics has recently ceased to be an exclusively medical problem. It affects an ever wider range of socio-economic aspects of the world community and, having reached a high level, grows into a global threat to the health of the world's population. In the course of evolution, bacteria have developed a number of effective strategies for protection against antimicrobial agents. This causes the paramount importance of developing promising strategies for finding alternative strategies for combating infectious diseases. In this review, the authors discuss and analyze several areas of searching for new drugs, potentially capable of becoming an alternative to traditional antibiotic therapy.

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The authors declare that there are no conflicts of interest present.