antibioticsАнтибиотики и ХимиотерапияAntibiot Khimioter = Antibiotics and Chemotherapy0235-2990ООО «Издательство ОКИ»antibiotics-69Research ArticleОБЗОРЫREVIEWSВакцинация в ревматологии: настоящее и будущееVaccination In Rheumatology: Present And FutureБеловБ. С.BelovB. S.noemail@neicon.ruБухановаД. В.BukhanovaD. V.noemail@neicon.ruТарасоваГ. М.TarasovaG. M.noemail@neicon.ruНИИ ревматологии им. В. А. НасоновойРоссияNasonova Research Institute of RheumatologyRussian Federation201806052020631-25668Copyright © Белов Б.С., Буханова Д.В., Тарасова Г.М., 20202020Белов Б.С., Буханова Д.В., Тарасова Г.М.Belov B.S., Bukhanova D.V., Tarasova G.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.antibiotics-chemotherapy.ru/jour/article/view/69

В ревматологии значимость коморбидных инфекций за последнее время существенно увеличилась, особенно в связи с внедрением в клиническую практику генно-инженерных биологических препаратов. Одним из путей решения указанной проблемы является изучение и активное применение различных вакцин. В настоящем обзоре рассмотрены вопросы, касающиеся применения вакцин против гриппа, инфекций, обусловленных пневмококками, вирусами герпеса, папилломы человека и гепатита В у ревматологических больных. Обсуждается безопасность и иммуногенность вакцинации, связанной с предупреждением инфекций дыхательных путей как наиболее частой причины неблагоприятного исхода при ревматических заболеваниях. Обозначены основные направления будущих исследований по рассматриваемой проблеме.

The significance of comorbid infections has significantly increased in rheumatology lately, especially in connection with the introduction of genetically engineered biological products into clinical practice. One way to solve this problem is to study and actively use various vaccines. This review examines issues related to the use of vaccines against influenza, pneumococcal infections, herpes viruses, human papillomavirus, and hepatitis B in rheumatological patients. The article discusses the safety and immunogenicity of vaccination associated with the prevention of respiratory tract infections as the most common cause of adverse outcome in rheumatological patients. The main directions of future research on the problem are indicated.

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The authors declare that there are no conflicts of interest present.