antibioticsАнтибиотики и ХимиотерапияAntibiot Khimioter = Antibiotics and Chemotherapy0235-2990ООО «Издательство ОКИ»10.37489/0235-2990-2021-66-9-10-64-78antibiotics-861Research ArticleОБЗОРЫREVIEWSНовое поколение пробиотиков — психобиотики, их назначение и функцииA new generation of probiotics — psychobiotics, their purpose and functionshttps://orcid.org/0000-0001-6997-7846ДбарС. Д.DbarS. D.

Дбар Сария Джоновна — аспирантка 2 курса кафедры микробиологии, биологического факультета

Москва

Sariya D. Dbar — 2nd year postgraduate student of the Microbiology Department

Moscow

СтояноваЛ. Г.StoyanovaL. G.

Стоянова Лидия Григорьевна – д. б. н., в. н. с. кафедры микробиологии, биологического факультета

Москва

Lidia G. Stoyanova — D.Sc. in biology

Moscow

stoyanovamsu@mail.ruФГБОУ ВО «Московский государственный университет им. М. В. Ломоносова»РоссияLomonosov Moscow State UniversityRussian Federation202102012022669-106478Copyright © Дбар С.Д., Стоянова Л.Г., 20222022Дбар С.Д., Стоянова Л.Г.Dbar S.D., Stoyanova L.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.antibiotics-chemotherapy.ru/jour/article/view/861

Представлен обзор литературы о этиологической роли микробиома в терапии депрессивных расстройств на основании анализа 98 источников литературы за 2000–2020 гг. из которых 35 отечественных и 63 зарубежных источников. Обоснованы доказательства того, что кишечный микробиом может представлять новую потенциальную антидепрессантную мишень. Появление нового класса пробиотиков (психобиотиков) и возможное психобиотическое лечение, могут стать многообещающей стратегией для улучшения качества жизни людей, страдающих нейродегенеративными заболеваниями и нарушениями развития нервной системы.

A review of the literature on the etiological role of the microbiome in the treatment of depressive disorders is presented based on an analysis of 98 literature sources for 2000–2020, of which 35 are domestic and 63 are foreign. Evidence is substantiated that the gut microbiome may represent a new potential target of antidepressant therapy. The emergence of a new class of probiotics (psychobiotics), as well as possible psychobiotic treatments, could be a promising strategy for improving the quality of life of people suffering from neurodegenerative diseases and developmental disorders of the nervous system.

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The authors declare that there are no conflicts of interest present.