antibioticsАнтибиотики и ХимиотерапияAntibiot Khimioter = Antibiotics and Chemotherapy0235-2990ООО «Издательство ОКИ»10.37489/0235-2990-2022-67-1-2-53-61antibiotics-890Research ArticleОБЗОРЫREVIEWSМетоды и подходы для определения антибиотиковMethods and Approaches for Antibiotics DeteсtionАлсовэйдиА. К. М.AlsowaidiA. K.M.

Алсовэйди Али  Кадхим Мохаммед —  аспирант  очной формы обучения.

Саратов.

Ali Kadhim Mohammed Alsowaidi — full-time  Ph. D. student, Saratov State University.

Saratov.

КараваеваО. А.KaravaevaO. A.

Караваева Ольга Александровна — кандидат биологических наук, научный  сотрудник лаборатории биохимии.

Саратов.

Olga A. Karavaeva — Ph. D. in biology, Institute of Biochemistry and Physiology of Plants and Microorganisms of the Russian Academy  of Sciences.

Saratov.

ГулийО. И.GuliyO. I.

Гулий Ольга Ивановна — доктор биологических наук, профессор, ведущий  научный сотрудник лаборатории биохимии ИБФРМ РАН; профессор кафедры микробиологии, биотехнологии и химии СГАУ им. Вавилова.

пр-т Энтузиастов, 13, Саратов, 410049.

Olga I. Guliy  — D. Sc. in biology, Professor, Institute  of Biochemistry  and  Physiology  of Plants  and  Microorganisms of the Russian Academy of Sciences, Saratov State Vavilov Agrarian University.

13 Entuziastov ave., Saratov, 410049.

guliy_olga@mail.ruСаратовский национальный исследовательский государственный университет им. Н.Г. ЧернышевскогоРоссияSaratov State UniversityRussian FederationИнститут биохимии и физиологии растений и микроорганизмов РАНРоссияInstitute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of SciencesRussian FederationИнститут биохимии и физиологии растений и микроорганизмов РАН; Саратовский государственный аграрный университет им. Н.И. ВавиловаРоссияInstitute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences; Saratov State Vavilov Agrarian UniversityRussian Federation202216042022671-25361Copyright © Алсовэйди А.К., Караваева О.А., Гулий О.И., 20222022Алсовэйди А.К., Караваева О.А., Гулий О.И.Alsowaidi A.K., Karavaeva O.A., Guliy O.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.antibiotics-chemotherapy.ru/jour/article/view/890

Антибактериальные препараты являются одними из самых важных лекарств, используемых в здравоохранении и ветеринарии. Широкое использование антибиотиков привело к значительному загрязнению окружающей среды и, особенно, водных ресурсов. В связи с этим актуальным является проблема контроля содержания антибиотиков в лекарственных формах, а также их определение в жидкостях, в продуктах питания, сточных водах фармацевтических предприятий и других  объектах. Для обнаружения антибиотиков используют микробиологические, спектрофотометрические, флуориметрические, хемилюминесцентные, хроматографические, а также биосенсорные методы. В статье приводится обзор методов и подходов для определения антибиотиков. Показан прогресс в разработке биосенсорных систем для анализа антибиотиков.

Antibacterial drugs are some of the most important medications used in health and veterinary medicine. The widespread use of antibiotics has led to significant pollution of the environment and water resources, in particular . In this regard, the problem of controlling antibiotic content in dosage forms, as well as their detection in liquids, food products, waste waters of pharmaceutical enterprises, and the other objects, is urgent. Microbiological, spectrophotometric, fluorimetric, chemiluminescent, chromatographic, as well as biodetection methods are used to identify antibiotics. The article provides a brief overview of methods and approaches for the detection of antibiotics. Progress in the development of biosensor systems for the analysis of antibiotics has been shown.

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The authors declare that there are no conflicts of interest present.