Preview

Antibiot Khimioter = Antibiotics and Chemotherapy

Advanced search

The Use of Negative Pressure Wound Therapy and Substrate Antihypoxant in the Treatment of an Elderly Polymorbid Patient (Clinical Observation)

https://doi.org/10.37489/0235-2990-2024-69-11-12-75-79

EDN: ZRUZWI

Abstract

The article presents a clinical observation of an elderly polymorbid patient with a complicated course of the underlying disease, which led to an expanded scope of surgical intervention. The effectiveness of inclusion in the complex treatment regimens of negative pressure wound therapy (NPWT systems in the mode of 120–160 mm Hg, 7-day course) and 1.5% reamberin infusions (400.0, intravenous drip, daily, general course No. 6) is shown. It manifested in the acceleration of reparative processes and a decrease in the area of the wound surface and contributed to the stabilization of the general condition of the patient: a decrease in the severity of clinical symptoms and vascular disorders. The obtained results can serve as a basis for a more in-depth study in this direction.

About the Author

M. V. Varganov
Izhevsk State Medical Academy
Russian Federation

Mikhail V. Varganov — D. Sc. in Medicine, Professor of the Department of Faculty Surgery.

Izhevsk


Competing Interests:

none



References

1. Sevostyanova E. V., Nikolaev Yu. A., Polyakov V. Yа. The problem of multimorbidity in a modern therapeutic clinic. Bulletin of Siberian Medicine. 2022; 21 (1): 162–170. doi: https://doi.org/10.20538/1682-0363-2022-1-162-170. (in. Russian)

2. Tarlovskaya E. I. Comorbidity and polymorbidity – modern interpretation and urgent tasks facing the therapeutic community. Cardiology. 2018; 58 (S9): 29–38. https://doi.org/10.18087/cardio.2562. (in Russian)

3. Shirinsky V. S., Shirinsky I. V. Polymorbidity, ageing of immune system and low-grade systemic inflammation: a challenge for modern medicine Medical Immunology. 2020; 22 (4): 609–624. https://doi.org/doi:10.15789/1563-0625-PAO-2042. (in Russian)

4. Obolenskij V. N., Ermolov A. A., Aronov L. S., Rodoman G. V., Serov R. A. Application of the method of local negative pressure in the complex treatment of acute purulent-inflammatory diseases of soft tissues. Hirurgija. Zhurnal im. N. I. Pirogova. 2012; 1: 50–55. (in Russian)

5. Varganov M. V., Miklichev A. A., Larin V. V. Npwt-therapy combined with reamberin infusion for gastroenterostomy failure after stomach resection. Pirogov Russian Journal of Surgery. 2019; (8): 91–94. doi: https://doi.org/10.17116/hirurgia201908191. (In Russian)

6. Miklichev A. A., Varganov M. V., Kuzyaev M. V., Shamshurina A. A. Combined application of NPWT-therapy and reamberin infusion in treatment of lower limb trophic ulcer (clinical case). Pirogov Russian Journal of Surgery. 2019; (1): 101–104. doi: https://doi.org/10.17116/hirurgia2019011101. (in Russian)

7. Reamberin: clinical and experimental studies. Abstract collection of scientific papers cited in PubMed. Belov V. G. (ed.), SPb.: 2013; 288. (in Russian)


Review

For citations:


Varganov M.V. The Use of Negative Pressure Wound Therapy and Substrate Antihypoxant in the Treatment of an Elderly Polymorbid Patient (Clinical Observation). Antibiot Khimioter = Antibiotics and Chemotherapy. 2024;69(11-12):75-79. (In Russ.) https://doi.org/10.37489/0235-2990-2024-69-11-12-75-79. EDN: ZRUZWI

Views: 678


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 0235-2990 (Print)