Evaluation of the Three-Component Drug Regimen (Glutamyl-Tryptophan + Bendazole + Ascorbic Acid) Preventive Efficacy for the Prevention of Influenza, Respiratory Viral Infections, and Pneumonia in the Context of Vaccination
https://doi.org/10.37489/0235-2990-2026-71-1-2-20-24
EDN: XFYPXZ
Abstract
Background. In the modern literature, ways to increase the effectiveness of specific prevention of acute respiratory viral infections and pneumonia, including through the use of immunostimulants, are widely discussed.
The aim of the study was to determine the epidemiological effectiveness of using the three-component drug regimen: glutamine-tryptophan + bendazole + ascorbic acid in combination with influenza and pneumococcal vaccines to reduce the incidence of acute respiratory infections and pneumonia.
Material and methods. Two groups (283 people) were examined after vaccination with Grippol and Pneumo 23. In the first group (140 people), a three-component drug regimen (glutamine-tryptophan + bendazole + ascorbic acid) was used in combination with vaccination. In the second group (143 people), preventive measures were limited to vaccination.
Results and discussion. The use of a three-component drug regimen for the prevention of acute respiratory viral infections in combination with Pneumo 23 and Grippol vaccination reduces the disease incidence by 3.3 times in the first month after the start of the treatment (epidemiological efficacy of 69.8%).
About the Authors
M. E. Meshkova
Military Medical Academy
Russian Federation
Competing Interests:
Russian Federation
Marina E. Meshkova — Ph. D. in Biology, Associate Professor, Department of Clinical Biochemistry and Laboratory Diagnostics
St. Petersburg
Competing Interests:
The authors declare no conflict of interest.
E. A. Malakhova
Military Medical Academy
Russian Federation
Competing Interests:
Russian Federation
Elena A. Malakhova — Lecturer at the Department of Clinical Biochemistry and Laboratory Diagnostics
St. Petersburg
Competing Interests:
The authors declare no conflict of interest.
I. A. Sukhina
Military Medical Academy
Russian Federation
Competing Interests:
Russian Federation
Irina A. Sukhina — Ph. D. in Biology, Lecturer at the Department of Clinical Biochemistry and Laboratory Diagnostics
St. Petersburg
Competing Interests:
The authors declare no conflict of interest.
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For citations:
Meshkova ME, Malakhova EA, Sukhina IA. Evaluation of the Three-Component Drug Regimen (Glutamyl-Tryptophan + Bendazole + Ascorbic Acid) Preventive Efficacy for the Prevention of Influenza, Respiratory Viral Infections, and Pneumonia in the Context of Vaccination. Antibiotiki i Khimioterapiya = Antibiotics and Chemotherapy. 2026;71(1-2):20-24. (In Russ.) https://doi.org/10.37489/0235-2990-2026-71-1-2-20-24. EDN: XFYPXZ
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