Results of a Cross-Sectional Multicenter Study of Antimicrobial Use in Tashkent Hospitals (GLOBAL-PPS)

The irrational use of antimicrobial agents in hospitals is a key factor in the development of antibiotic resistance. Regular monitoring of antimicrobial use makes it possible to optimize pharmacotherapy and identify factors contributing to the rise of antibiotic resistance.

The aim of the study was to examine the practice of prescribing antimicrobial drugs to hospitalized patients based on the results of the Global Point Prevalence Survey (Global-PPS) conducted in Tashkent hospitals.

Materials and methods. The study covered three inpatient facilities. The analysis included 54 hospitalized patients undergoing treatment at the time of the assessment. At the facility P1 (the clinic of the Republican Specialized Scientific-Practical Medical Center of Epidemiology, Microbiology and Infectious Diseases), 26 patients receiving treatment in the Infectious Disease and Intensive Care Units were examined. At the R3 inpatient facility (City Clinical Hospital), the study was conducted in the Urology Department. At the R4 inpatient facility (Republican Specialized Scientific-Practical Medical Center of Pediatrics), 28 patients hospitalized in two Pediatric Departments were examined.

Conclusion. The results of the study can be used to improve the prescription of antimicrobial agents in each of the participating hospitals, as well as to monitor the effectiveness of antimicrobial stewardship activities.

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