Opportunities and Perspectives of the Use of Cytoflavin for Increasing the Adaptational Reserves of Experts Working in the Mountain Conditions
          
      
    
      
    
                        
              https://doi.org/10.24411/0235-2990-2019-100031
        
          
    
  
      
  
    
                
            Abstract
            When carrying out professional activities of specialists in mountainous conditions associated with physical and psycho-emotional stress, measures aimed at adapting the body to high altitude hypoxia, such as conducting hypoxic training both in natural mountainous areas and modeling hypoxic hypoxia using hypobaric chambers or hypoxicators simulating normobaric hypoxia and the use of pharmacological correction that allows ro mobilize either economize resources of the organism. The antihypoxant / antioxidant cytoflavin, successfully used in the treatment of diseases of the nervous system, is supposed to be used to improve physical performance and psychomotor functions among professionals working in mountainous areas. The authors conducted a pilot study with the participation of climbers, who completed a course of hypoxic hypobaric training with the pharmacocorrection of trecresan and cytoflavin. Revealed a tendency to increase the level and concentration of attention in athletes who received pharmacocorrection, in contrast to taking placebo. The identified positive trends in psychomotor performance combined with good tolerability of the drug are the basis for planning further research.
         
              
        
                  
		  Conflicts of Interest Disclosure:
		  The authors declares that there is no conflict of interest.
       
              
		  Article info:
		  Date submitted: 06.05.2020
		  		  		         
              
                  All authors have read and approved the final manuscript.
        
       
              
		  Peer review info:
		  "Antibiot Khimioter = Antibiotics and Chemotherapy" thanks the anonymous reviewer(s) for their contribution to the peer review of this work.
       
    	      
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                  About the Authors
              
               
             V. P. Ganapolskiy
         
        
                        S. M. Kirov Military medical academy
        
Russian Federation
    
				    
    
    
             
             V. O. Matytsin
         
        
                        S. M. Kirov Military medical academy
        
Russian Federation
    
				    
    
    
             
             S. S. Grinchuk
         
        
                        S. M. Kirov Military medical academy
        
Russian Federation
    
				    
    
    
             
             A. N. Yatmanov
         
        
                        S. M. Kirov Military medical academy
        
Russian Federation
    
				    
    
    
             
             V. F. Lopatina
         
        
                        S. M. Kirov Military medical academy
        
Russian Federation
    
				    
    
    
             
             V. A. Zaplutanov
         
        
                        Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of Sciences
        
Russian Federation
    
				    
    
    
          
     
        
    
    
    
 
    
      For citations:
                                    Ganapolskiy VP, 
                                Matytsin VO, 
                                Grinchuk SS, 
                                Yatmanov AN, 
                                Lopatina VF, 
                                Zaplutanov VA.
                                              Opportunities and Perspectives of the Use of Cytoflavin for Increasing the Adaptational Reserves of Experts Working in the Mountain Conditions.      Antibiotiki i Khimioterapiya = Antibiotics and Chemotherapy.            2019;64(5-6):49-53.  
                                                                                                      (In Russ.)
                                          
                                                  https://doi.org/10.24411/0235-2990-2019-100031                          
    
  
  
  
  
    
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