In vitro Activity of Luromarin Against Tick-Borne Encephalitis Virus
Abstract
Luromarin, extracted from the sea alga Zostera asiatica, showed no cytotoxic activity when incubated with the SPEV cell culture and was characterized by virulicidal properties against highly pathogenic strain of TBE virus and the ability to inhibit the virus replication at the early stages of the infection.
About the Authors
N. V. Krylova
Research Institute of Epidemiology and Microbiology of the Siberian Branch of the Russian Academy of Medical Sciences
Russian Federation
Russian Federation
G. N. Leonova
Research Institute of Epidemiology and Microbiology of the Siberian Branch of the Russian Academy of Medical Sciences
Russian Federation
Russian Federation
O. S. Maistrovskaya
Research Institute of Epidemiology and Microbiology of the Siberian Branch of the Russian Academy of Medical Sciences
Russian Federation
Russian Federation
A. M. Popov
Pacific Institute of Bioorganic Chemistry, Ear-East Branch of the Russian Academy of Sciences
Russian Federation
Russian Federation
A. A. Artyukov
Pacific Institute of Bioorganic Chemistry, Ear-East Branch of the Russian Academy of Sciences
Russian Federation
Russian Federation
E. P. Kozlovskaya
Pacific Institute of Bioorganic Chemistry, Ear-East Branch of the Russian Academy of Sciences
Russian Federation
Russian Federation
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Review
For citations:
Krylova N.V., Leonova G.N., Maistrovskaya O.S., Popov A.M., Artyukov A.A., Kozlovskaya E.P. In vitro Activity of Luromarin Against Tick-Borne Encephalitis Virus. Antibiot Khimioter = Antibiotics and Chemotherapy. 2010;55(7-8):17. (In Russ.)
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