Investigation of Luromarin Efficacy on Mice with Experimental Tick-Borne Encephalitis
Abstract
Oral use of Luromarin, extracted from sea algae Zostera asiatica, was efficient In protection of mice from lethal infection induced by highly pathogenic strain of TBE virus, by extending their average lifespan. Luromarin demonstrated potentiating action in combination with ribavirin and cycloferon.
About the Authors
N. V. Krylova
НИИ эпидемиологии и микробиологии СО РАМН
Russian Federation
Russian Federation
G. N. Leonova
НИИ эпидемиологии и микробиологии СО РАМН
Russian Federation
Russian Federation
A. M. Popov
Тихоокеанский институт биоорганической химии ДВО РАН
Russian Federation
Russian Federation
A. A. Artyukov
Тихоокеанский институт биоорганической химии ДВО РАН
Russian Federation
Russian Federation
E. P. Kozlovskaya
Тихоокеанский институт биоорганической химии ДВО РАН
Russian Federation
Russian Federation
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Review
For citations:
Krylova N.V., Leonova G.N., Popov A.M., Artyukov A.A., Kozlovskaya E.P. Investigation of Luromarin Efficacy on Mice with Experimental Tick-Borne Encephalitis. Antibiot Khimioter = Antibiotics and Chemotherapy. 2011;56(7-8):13-15. (In Russ.)
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