EFFICACY OF AZITHROMYCIN AND ITS IMPACT IN CYTOKINE SYSTEM IN UROGENITAL INFECTIONS
Abstract
Seventy five patients with urogenital chlamydial and mycoplasmic infections were enrolled in the trial. In the etiotropic therapy azithromycin was used in the standard dosage (1.0-1.5 g) depending on the infection. The treatment with azithromycin, in addition to the high eradication rates, was also evident of its effect on the cytokine levels in the patients, that was characteristic of a significant increase of the IFN-γ level and a decrease of the IL-β and IL-6 levels in the blood.
About the Authors
A. A. Khryanin
Novosibirsk State Medical University
Russian Federation
Russian Federation
O. V. Reshetnikov
Research Institute of Therapy, Siberian Branch of Russian Academy of Medical Sciences
Russian Federation
Russian Federation
I. D. Safronov
Novosibirsk State Medical University; Scientific Centre of Clinical and Experimental Medicine, Siberian Branch of Russian Academy of Medicals Sciences
Russian Federation
Russian Federation
A. N. Trunov
Scientific Centre of Clinical and Experimental Medicine, Siberian Branch of Russian Academy of Medicals Sciences
Russian Federation
Russian Federation
N. B. Kulikova
Novosibirsk State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Khryanin A.A., Reshetnikov O.V., Safronov I.D., Trunov A.N., Kulikova N.B. EFFICACY OF AZITHROMYCIN AND ITS IMPACT IN CYTOKINE SYSTEM IN UROGENITAL INFECTIONS. Antibiot Khimioter = Antibiotics and Chemotherapy. 2012;57(3-4):29-32. (In Russ.)
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