Antibiotic-Resistant Uropathogenic Escherichia coli Isolated from Children with Congenital Abnormalities of the Kidneys and Urinary Tract
https://doi.org/10.37489/0235-2990-2020-65-7-8-23-26
Abstract
Uropathogenic Escherichia coli (UPEC) is a serious health problem worldwide. UPEC's multiple drug resistance combined with virulence factors is a cause of serious concern. In childhood, urinary tract infections are of particular importance, since they can occur against the background of long-term unrecognized congenital anomalies of the kidneys and urinary tract. Of the 106 UPEC clinical isolates, 63.2% of cultures were isolated from girls' urine samples and 36.8% from boys' urine samples, which corresponds to a 1.7: 1 ratio. The antibiotic resistance of the isolated UPEC cultures was assessed in relation to 12 antimicrobial drugs. Among the tested cultures, 49% were multidrug-resistant and 20.75% were found to be resistant to imipenem. Phenotypic analysis of antibiotic susceptibility spectrum of uropathogenic E.coli (n=106) indicates a high percentage of occurrence of multi-resistant UPEC strains (49%) and imipenem-resistant UPEC strains (20.75%) among children of all age groups.
About the Authors
S. Suadkia
RUDN University
Russian Federation
Moscow
Russian Federation
Moscow
I. V. Podoprigora
RUDN University
Russian Federation
Moscow
Russian Federation
Moscow
N. V. Yashina
RUDN University
Russian Federation
Moscow
Russian Federation
Moscow
L. E. Sarukhanova
RUDN University
Russian Federation
Moscow
Russian Federation
Moscow
E. G. Kravtsov
RUDN University
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Suadkia S., Podoprigora I.V., Yashina N.V., Sarukhanova L.E., Kravtsov E.G. Antibiotic-Resistant Uropathogenic Escherichia coli Isolated from Children with Congenital Abnormalities of the Kidneys and Urinary Tract. Antibiot Khimioter = Antibiotics and Chemotherapy. 2020;65(7-8):23-26. (In Russ.) https://doi.org/10.37489/0235-2990-2020-65-7-8-23-26
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