Changes in the Etiological Structure and Specifics When Choosing Antibacterial Therapy Against Infective Endocarditis in Pediatric Practice
https://doi.org/10.37489/0235-2990-2023-68-7-8-78-82
Abstract
Infective endocarditis in children is a rare disease, which often has an extremely serious prognosis. The most common risk factor for infective endocarditis in this category of patients is the history of congenital heart disease. At the same time, currently, the disruption of the integrity of the peripheral vascular bed is increasingly noted, among the predisposing causes, due to invasive diagnostic and therapeutic medical procedures, as well as severe somatic diseases. In accordance with the developed recommendations, the appointment of antibacterial therapy for infective endocarditis should be based on etiotropic orientation. Taking these circumstances into account, the article presents an overview of the data reflecting the issues of etiology and choice of antibacterial therapy for infective endocarditis in pediatric practice.
About the Authors
А. I. Danilov
Smolensk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Andrey I. Danilov — Ph. D. in Medicine, Associate Professor of the Department of Clinical Pharmacology
28 Krupskoy st., Smolensk, 214019
А. V. Evseev
Smolensk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Andrey V. Evseev — D. Sc. in Medicine, Professor, Head of the Research Center, Head of the Department of Normal Physiology
Smolensk
Т. G. Avdeeva
Smolensk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Tatyana G. Avdeeva — D. Sc. in Medicine, Professor of the Department of Outpatient Pediatrics
Smolensk
Т. I. Legonkova
Smolensk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Tatyana I. Legonkova — D. Sc. in Medicine, Professor, Head of the Department of Propaedeutics of Childhood Diseases and Faculty Pediatrics
Smolensk
L. Р. Zharkova
Smolensk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Lyudmila P. Zharkova — D. Sc. in Medicine, Professor, Department of clinical pharmacology
Smolensk
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Review
For citations:
Danilov А.I., Evseev А.V., Avdeeva Т.G., Legonkova Т.I., Zharkova L.Р. Changes in the Etiological Structure and Specifics When Choosing Antibacterial Therapy Against Infective Endocarditis in Pediatric Practice. Antibiot Khimioter = Antibiotics and Chemotherapy. 2023;68(7-8):78-82. (In Russ.) https://doi.org/10.37489/0235-2990-2023-68-7-8-78-82
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