Нанокапсулированные системы: перспективные биомедицинские инициативы в фармакологии
https://doi.org/10.37489/0235-2990-2024-69-3-4-62-72
EDN: GNCNIG
Аннотация
Важнейшим направлением современной фармакологии является исследование систем, используемых для контролируемой и целенаправленной адресной доставки лекарственных препаратов, которое реализуется путём создания нанокапсулированных форм, имеющих различную природу и химическое строение. Нанокапсулирование — перспективный метод создания инновационных лекарственных форм с пролонгированным действием, позволяющий расширить номенклатуру лекарственных средств и изменить подходы к лечению различных заболеваний, требующих длительной терапии. В данном обзоре представлена информация, освещающая наиболее перспективные классы наноразмерных носителей лекарственных средств, описаны технологические процессы их получения на основе липидов, полимеров и биодеградируемых минеральных веществ, а также приведены примеры использования в современной фармацевтической практике.
Ключевые слова
При поддержке: Работа выполнена в рамках государственного задания (№ 124020300056-9) Министерства здравоохранения Российской Федерации в части проведения НИР по теме «Поиск и разработка высокостабильной липосомальной системы для инкапсулирования соединений с потенциальной антибактериальной активностью на примере хиназолиновых производных, активных в отношении S. aureus».
Об авторах
Г. Н. Генатуллина
Астраханский государственный медицинский университет
Россия
Россия
Генатуллина Гузель Наилевна — к. б. н., заместитель руководителя Научно-исследовательского центра; доцент кафедры фармакогнозии, фармацевтической технологии и биотехнологии
Астрахань
А. Л. Ясенявская
Астраханский государственный медицинский университет
Россия
Россия
Ясенявская Анна Леонидовна — к. м. н., доцент, руководитель Научно-исследовательского центра; доцент кафедры фармакогнозии, фармацевтической технологии и биотехнологии
Астрахань
А. А. Цибизова
Астраханский государственный медицинский университет
Россия
Россия
Цибизова Александра Александровна — к. фарм. н., доцент кафедры фармакогнозии, фармацевтической технологии и биотехнологии
Астрахань
М. А. Самотруева
Астраханский государственный медицинский университет
Россия
Россия
Самотруева Марина Александровна — д. м. н., профессор, заведующая кафедрой фармакогнозии, фармацевтической технологии и биотехнологии
Астрахань
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Рецензия
Для цитирования:
Генатуллина Г.Н., Ясенявская А.Л., Цибизова А.А., Самотруева М.А. Нанокапсулированные системы: перспективные биомедицинские инициативы в фармакологии. Антибиотики и Химиотерапия. 2024;69(3-4):62-72. https://doi.org/10.37489/0235-2990-2024-69-3-4-62-72. EDN: GNCNIG
For citation:
Genatullina G.N., Yasenyavskaya A.L., Tsibizova A.A., Samotrueva M.A. Nanoencapsulated Systems: Promising Biomedical Initiatives in Pharmacology. Antibiot Khimioter = Antibiotics and Chemotherapy. 2024;69(3-4):62-72. (In Russ.) https://doi.org/10.37489/0235-2990-2024-69-3-4-62-72. EDN: GNCNIG
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