Studying the Effectiveness of Ridostin® in the Experimental Form of Severe Acute Respiratory Syndrome
https://doi.org/10.1016/0235-2990-2019-64-11-12-31-34
Abstract
Studies have been carried out on the effectiveness of the high molecular weight interferon inducer Ridostin® in relation to the experimental form of severe acute respiratory syndrome in Syrian hamsters. It is shown that Ridostin® is effective when used according to the prophylaxis regimen and post-exposure prophylaxis regimen. The coefficient of therapeutic effect was 47.5 and 55.0%, respectively. At the same time, there was a statistically high level of significant differences in the severity of the disease in animals treated with the medication according to the post-exposure prophylaxis regimen and control animals (P<0.05).
Conflicts of Interest Disclosure:
The authors declares that there is no conflict of interest.
Article info:
Date submitted: 06.05.2020
All authors have read and approved the final manuscript.
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"Antibiot Khimioter = Antibiotics and Chemotherapy" thanks the anonymous reviewer(s) for their contribution to the peer review of this work.
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About the Authors
S. Ya. Loginova
48 Central Scientific Research Institute of the Ministry of Defence of the Russian Federation
Russian Federation
V. N. Shchukina
48 Central Scientific Research Institute of the Ministry of Defence of the Russian Federation
Russian Federation
S. V. Borisevich
48 Central Scientific Research Institute of the Ministry of Defence of the Russian Federation
Russian Federation
R. A. Hamitov
OOO International Biotechnology Center «Generium»
Russian Federation
V. A. Maksimov
48 Central Scientific Research Institute of the Ministry of Defence of the Russian Federation
Russian Federation
For citations:
Loginova S.Ya.,
Shchukina V.N.,
Borisevich S.V.,
Hamitov R.A.,
Maksimov V.A.
Studying the Effectiveness of Ridostin® in the Experimental Form of Severe Acute Respiratory Syndrome. Antibiot Khimioter = Antibiotics and Chemotherapy. 2019;64(11-12):31-34.
(In Russ.)
https://doi.org/10.1016/0235-2990-2019-64-11-12-31-34
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