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Studying the Effectiveness of Ridostin® in the Experimental Form of Severe Acute Respiratory Syndrome

https://doi.org/10.1016/0235-2990-2019-64-11-12-31-34

Abstract

Studies have been carried out on the effectiveness of the high molecular weight interferon inducer Ridostin® in relation to the experimental form of severe acute respiratory syndrome in Syrian hamsters. It is shown that Ridostin® is effective when used according to the prophylaxis regimen and post-exposure prophylaxis regimen. The coefficient of therapeutic effect was 47.5 and 55.0%, respectively. At the same time, there was a statistically high level of significant differences in the severity of the disease in animals treated with the medication according to the post-exposure prophylaxis regimen and control animals (P<0.05).

About the Authors

S. Ya. Loginova
48 Central Scientific Research Institute of the Ministry of Defence of the Russian Federation
Russian Federation


V. N. Shchukina
48 Central Scientific Research Institute of the Ministry of Defence of the Russian Federation
Russian Federation


S. V. Borisevich
48 Central Scientific Research Institute of the Ministry of Defence of the Russian Federation
Russian Federation


R. A. Hamitov
OOO International Biotechnology Center «Generium»
Russian Federation


V. A. Maksimov
48 Central Scientific Research Institute of the Ministry of Defence of the Russian Federation
Russian Federation


Review

For citations:


Loginova S.Ya., Shchukina V.N., Borisevich S.V., Hamitov R.A., Maksimov V.A. Studying the Effectiveness of Ridostin® in the Experimental Form of Severe Acute Respiratory Syndrome. Antibiot Khimioter = Antibiotics and Chemotherapy. 2019;64(11-12):31-34. (In Russ.) https://doi.org/10.1016/0235-2990-2019-64-11-12-31-34

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ISSN 0235-2990 (Print)