Algae and Type 2 Diabetes: New Treatment Strategies
          
      
    
      
    
                        
              https://doi.org/10.1016/0235-2990-2019-64-11-12-54-67
        
          
    
  
      
  
    
                
            Abstract
            The review contains recent materials on the effects of extracts, polysaccharides, and polyphenols from brown algae in type 2 diabetes mellitus, which are a potential basis for creating effective antihyperglycemic agents. These biologically active substances are polyvalent biomodulators that have a multi-component effect in diabetes. These biopolymers reduce blood glucose levels, increase insulin production, decrease insulin resistance, inhibit α-amylase and α-glucosidase production, have antioxidant and anti-inflammatory activity, protect pancreatic, liver, and kidney tissues from high glucose concentrations. Algae are promising candidates for creating new generation drugs with associated activity, functional foods and dietary supplements for use in type 2 diabetes mellitus.
         
              
        
                  
		  Conflicts of Interest Disclosure:
		  The authors declares that there is no conflict of interest.
       
              
		  Article info:
		  Date submitted: 06.05.2020
		  		  		         
              
                  All authors have read and approved the final manuscript.
        
       
              
		  Peer review info:
		  "Antibiot Khimioter = Antibiotics and Chemotherapy" thanks the anonymous reviewer(s) for their contribution to the peer review of this work.
       
    	      
		  Editorial comment:
		  In case of any discrepancies in a text or the differences in its layout between the pdf-version of an article and its html-version the priority is given to the pdf-version.
       
    	
                     
    
      
                  About the Authors
              
               
             N. N. Besednova
         
        
                        Somov Research Institute of Epidemiology and Microbiology
        
Russian Federation
    
				    
    
    
             
             S. P. Ermakova
         
        
                        G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences
        
Russian Federation
    
				    
    
    
             
             T. A. Kuznetsova
         
        
                        Somov Research Institute of Epidemiology and Microbiology
        
Russian Federation
    
				    
    
    
             
             I. D. Makarenkova
         
        
                        Somov Research Institute of Epidemiology and Microbiology
        
Russian Federation
    
				    
    
    
             
             S. P. Krizhanovsky
         
        
                        Medical Association of the Far Eastern Branch of the Russian Academy of Sciences
        
Russian Federation
    
				    
    
    
             
             B. G. Andryukov
         
        
                        Somov Research Institute of Epidemiology and Microbiology
        
Russian Federation
    
				    
    
    
             
             T. S. Saporozhets
         
        
                        Somov Research Institute of Epidemiology and Microbiology
        
Russian Federation
    
				    
    
    
          
     
        
    
    
    
 
    
      For citations:
                                    Besednova NN, 
                                Ermakova SP, 
                                Kuznetsova TA, 
                                Makarenkova ID, 
                                Krizhanovsky SP, 
                                Andryukov BG, 
                                Saporozhets TS.
                                              Algae and Type 2 Diabetes: New Treatment Strategies.      Antibiotiki i Khimioterapiya = Antibiotics and Chemotherapy.            2019;64(11-12):54-67.  
                                                                                                      (In Russ.)
                                          
                                                  https://doi.org/10.1016/0235-2990-2019-64-11-12-54-67                          
    
  
  
  
  
    
          Views: 
      2318