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Immunomodulators in Maintenance Therapy of Tuberculosis With Its Patomorphosis Features Taken Into Consideration

https://doi.org/10.1016/0235-2990-2019-64-11-12-68-71

Abstract

One of the fundamental features of tuberculosis pathomorphism in modern conditions is secondary immune deficiency, which manifests itself at the initial stage of the infection process and aggravates as the disease progresses. This review presents analysis results of cumulative clinical and laboratory data, confirming high efficiency of cycloferon as a support drug in the treatment of newly diagnosed tuberculosis forms and in patients with advanced forms, which allows recommending its inclusion in the treatment regimens of these disease forms. The effectiveness of the drug in treatment of comorbid tuberculosis and features of its non-specific prophylaxis require further research.

About the Authors

V. M. Kolomiets
Kursk State Medical University
Russian Federation


A. L. Kovalenko
Institute of Toxicology of the Federal Medico-biological Agency
Russian Federation


E. V. Talikova
Saint-Petersburg Medico-Social Institute
Russian Federation


Review

For citations:


Kolomiets V.M., Kovalenko A.L., Talikova E.V. Immunomodulators in Maintenance Therapy of Tuberculosis With Its Patomorphosis Features Taken Into Consideration. Antibiot Khimioter = Antibiotics and Chemotherapy. 2019;64(11-12):68-71. (In Russ.) https://doi.org/10.1016/0235-2990-2019-64-11-12-68-71

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ISSN 0235-2990 (Print)