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Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus

https://doi.org/10.24411/0235-2990-2019-10057

Abstract

The article presents an analysis of research evaluating the effectiveness of nonspecific means of emergency prevention and treatment of Ebola virus disease. It considers the most significant results of preclinical and clinical trials of nonspecific therapeutics for the causative agent of Ebola hemorrhagic fever, as well as the prospects for their use in healthcare practice at present. It has been established that the general tendency to create nonspecific means of prevention and treatment of Ebola virus disease is not the development of new drugs, but the attempts to detect the antiviral activity of already known drugs that previously had a different purpose. Favipiravir is considered as the most effective nonspecific therapeutic against Ebola virus disease.

About the Authors

T. E. Sizikova
FSBI 48 Central Research Institute of the Ministry of Defense of the Russian Federation
Russian Federation


v. N. Lebedev
FSBI 48 Central Research Institute of the Ministry of Defense of the Russian Federation
Russian Federation


A. A. Petrov
FSBI 48 Central Research Institute of the Ministry of Defense of the Russian Federation
Russian Federation


S. V. Borisevich
FSBI 48 Central Research Institute of the Ministry of Defense of the Russian Federation
Russian Federation


Review

For citations:


Sizikova T.E., Lebedev v.N., Petrov A.A., Borisevich S.V. Evaluation of the Effectiveness of Nonspecific Medical Protection Against Diseased, Caused of Ebola Virus. Antibiot Khimioter = Antibiotics and Chemotherapy. 2019;64(9-10):50-55. (In Russ.) https://doi.org/10.24411/0235-2990-2019-10057

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ISSN 0235-2990 (Print)