Preview

Antibiot Khimioter = Antibiotics and Chemotherapy

Advanced search

Highly Efficient Chemoprophylaxis of Perinatal Transmission of HIV 1 Infection in HIV-Infected Pregnant Women

Abstract

Prevention of HIV infection perinatal transmission with specific anti-HIV agents is at present effective and resultant. The use of retrovir and nevirapin in such cases is well known and approved. The Russian anti-HIV drug nicavir (phosphazide) also proved its high efficacy, that was evident from the results of its use in chemoprophylaxis of perinatal HIV infection transmission in HIV-infected pregnant women. The discussion of the results is presented.

About the Author

G. A. Galegov
D.I. Ivanovsky Research Institute of Virology, Russian Academy of Medical Sciences, Moscow; I.M. Sechenov Moscow Medical Academy
Russian Federation


References

1. Barlett J.G., Gallant J.E. Medical management of HIV infection. Publ John Hopkins University, Baltimore, USA, 2006; 469.

2. Watts D.H. Managing Pregnant Patients. AIDS Therapy. / Ed R. Dolin, H. Mazur, M. Saag. London, 2005.

3. Покровский В.В., Ермак Т.H., Беляева В.В., Юрин О.Г. ВИЧ-инфекция. Клиника, диагностика, лечение. М.: 2000; 568.

4. Галегов Г.А. Никавир (фосфазид) - антиретровирусный препарат: антиВИЧ-активность, токсикология, фармакокинетика и некоторые перспективы клинического применения. Антибиот. и химиотер. 2004; 49, 7: 3-8.

5. Krayevsky A.A., Watanabe K.A. Modified nucleosides as anti-AIDS drugs: current status and perspectives. M.: 1993; 212.

6. Кравченко А.В. Применение никавира в составе антиретровирусной терапии. Мед. каф. 2004; 2: 88-97.

7. Наркевич М.И. Чтобы остановить ВИЧ-эпидемию в России, требуются объединенные усилия государства и общественных организаций. ШАГИ профессионал, 2007; 1: 34-39.

8. Machardo J., Salomon H., Olivera M. et al. Antiviral activity and resistance profile of phosphazide, a novel prodrug of AZT. Nucleosides & Nucleotides. 1999; 18: 901-906.


Review

For citations:


Galegov G.A. Highly Efficient Chemoprophylaxis of Perinatal Transmission of HIV 1 Infection in HIV-Infected Pregnant Women. Antibiot Khimioter = Antibiotics and Chemotherapy. 2009;54(3-4):58-60. (In Russ.)

Views: 332


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 0235-2990 (Print)