Effect of Exogenic Proteolytic Enzymes on Transfer of Plasmid Genes in Mixed Bacterial Biofilms
Abstract
The effect of the enzyme complex from Vobenzin on transfer of plasmid genes In biofilms of gramnegative bacteria was studied. The extracellular matrix of the bacterial biofilms was shown to contain extracellular DNA carrying the antibiotic resistance markers. The action of the enzyme complex resulted in lower frequency of the antibiotic resistance genes transfer in mixed bacterial biofilms.
About the Authors
G. V. Tets
Academician I. P. Pavlov St.Petersburg State Medical University; St.Petersburg Academy of Postgraduate Medical Training
Russian Federation
Russian Federation
N. K. Artemenko
Academician I. P. Pavlov St.Petersburg State Medical University; St.Petersburg Academy of Postgraduate Medical Training
Russian Federation
Russian Federation
N. V. Zaslavskaya
Academician I. P. Pavlov St.Petersburg State Medical University; St.Petersburg Academy of Postgraduate Medical Training
Russian Federation
Russian Federation
K. L. Artemenko
Academician I. P. Pavlov St.Petersburg State Medical University; St.Petersburg Academy of Postgraduate Medical Training
Russian Federation
Russian Federation
G. YU. Knorring
Academician I. P. Pavlov St.Petersburg State Medical University; St.Petersburg Academy of Postgraduate Medical Training
Russian Federation
Russian Federation
V. V. Tets
Academician I. P. Pavlov St.Petersburg State Medical University; St.Petersburg Academy of Postgraduate Medical Training
Russian Federation
Russian Federation
YU. I. Sternin
Academician I. P. Pavlov St.Petersburg State Medical University; St.Petersburg Academy of Postgraduate Medical Training
Russian Federation
Russian Federation
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Review
For citations:
Tets G.V., Artemenko N.K., Zaslavskaya N.V., Artemenko K.L., Knorring G.Yu., Tets V.V., Sternin Yu.I. Effect of Exogenic Proteolytic Enzymes on Transfer of Plasmid Genes in Mixed Bacterial Biofilms. Antibiot Khimioter = Antibiotics and Chemotherapy. 2009;54(9-10):3-5. (In Russ.)
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