Investigation of in vitro Activity of Ingavirin® Against Influenza Virus A (H3N2)
Abstract
The comparative analysis of the efficacy of Ingavirin® and etiotropic chemotherapeutics, such as Arbidol® and Remantadin®, against the influenza virus A (H3N2) performed with the use of susceptible permanent cell cultures showed that in the used concentrations Ingavirin® was efficient in inhibition of the virus cytopathic activity , formation of the specific hemagglutinin and reproduction of the virus (by the accumulation).
About the Authors
S. YA. Loginova
Virological Centre of the Central Research Institute No. 48 of the Ministry of Defense of the Russian Federation, Sergiev Posad
Russian Federation
Russian Federation
S. V. Borisevich
Virological Centre of the Central Research Institute No. 48 of the Ministry of Defense of the Russian Federation, Sergiev Posad
Russian Federation
Russian Federation
I. V. Semenova
Virological Centre of the Central Research Institute No. 48 of the Ministry of Defense of the Russian Federation, Sergiev Posad
Russian Federation
Russian Federation
V. A. Maksimov
Virological Centre of the Central Research Institute No. 48 of the Ministry of Defense of the Russian Federation, Sergiev Posad
Russian Federation
Russian Federation
V. P. Bondarev
Virological Centre of the Central Research Institute No. 48 of the Ministry of Defense of the Russian Federation, Sergiev Posad
Russian Federation
Russian Federation
V. E. Nebolsin
Valenta Pharmacevtica, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Loginova S.Ya., Borisevich S.V., Semenova I.V., Maksimov V.A., Bondarev V.P., Nebolsin V.E. Investigation of in vitro Activity of Ingavirin® Against Influenza Virus A (H3N2). Antibiot Khimioter = Antibiotics and Chemotherapy. 2009;54(9-10):23-26. (In Russ.)
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