Physico-Chemical Properties and Structure of Oligomycin SC-II, Produced by Streptomyces virginiae 17
Abstract
Under the screening programme for antibiotics with antifungal and immunosuppressive activities, Streptomyces virginiae 17 producing an oligomycin complex was isolated. Separation of the complex by HPLC showed that it contained two components at a ratio of 8:2. The physico-chemical characteristics of the components were investigated. The structure of oligomycin was assessed by13C NMR and1H NMR.
About the Authors
A. N. Danilenko
N. M. Emmanuel Institute of Biochemical Physics, Russian Academy of Sciences
Russian Federation
Russian Federation
M. V. Bibikova
Viorin Co.
Russian Federation
Russian Federation
I. A. Spiridonova
Viorin Co.
Russian Federation
Russian Federation
N. E. Grammatikova
Olfarm Co.
Russian Federation
Russian Federation
A. V. Katlinsky
Microgen Co.
Russian Federation
Russian Federation
References
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Review
For citations:
Danilenko A.N., Bibikova M.V., Spiridonova I.A., Grammatikova N.E., Katlinsky A.V. Physico-Chemical Properties and Structure of Oligomycin SC-II, Produced by Streptomyces virginiae 17. Antibiot Khimioter = Antibiotics and Chemotherapy. 2012;57(11-12):3-7. (In Russ.)
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