Immune Disturbances in Patients with Postnecrotic Pseudocysts of the Pancreas
Abstract
The aim of the study was to investigate the role of immune disturbances in development of postnecrotic pseudocysts of the pancreas. 94 patients including 74 with postnecrotic pancreatitis and pseudocysts of the pancreas were observed. The adaptive reactions and subpopulation composition of the peripheral blood lymphocytes were assayed. The percentage of the cells in the state of apoptosis in the cyst content was estimated. The disturbances in the subpopulation composition of the lymphocytes and stress adaptive reactions of the blood system were shown to be some of the main pathogenetic factors in development of postnecrotic complications of pancreatitis. The data are useful in differential diagnosis of pseudocysts and choice of the optimal tactics in the operative treatment of such patients.
About the Authors
S. V. Morozov
Clinical Medical Surgical Centre; Omsk State Medical Academy
Russian Federation
Russian Federation
V. L. Poluektov
Clinical Medical Surgical Centre; Omsk State Medical Academy
Russian Federation
Russian Federation
V. T. Dolgikh
Clinical Medical Surgical Centre; Omsk State Medical Academy
Russian Federation
Russian Federation
A. B. Reis
Clinical Medical Surgical Centre; Omsk State Medical Academy
Russian Federation
Russian Federation
A. V. Ershov
Clinical Medical Surgical Centre; Omsk State Medical Academy
Russian Federation
Russian Federation
B. A. Reis
Clinical Medical Surgical Centre; Omsk State Medical Academy
Russian Federation
Russian Federation
References
1. Гарелик П. В., Довнар И. С., Полынский A. A., Пакульневич Ю. Ф. Современные технологии в лечении острых кист поджелудочной железы Анналы хирур гепатол 2007; 12: 3: 174-176.
2. Шабунин A. В. Панкреатоскопия в диагностике кистозных образований поджелудочной железы. Мед визуал 2001; 1: 18-22.
3. Вилявин Г. Д., Кочиашвили В. И., Калтаев К. К. Кисты и свищи поджелудочной железы. М.: 1977.
4. Гостищев В. К., Aфанасьев A. H., Устименко A. В. Диагностика и лечение постнекротических кист поджелудочной железы. Хирургия 2006; 6: 4-7.
5. Flautner L. E. New techniques in the management of pancreatic pseudocysts. Surg Today 1996; 26: 7: 552-555.
6. Баранов Е. В., Федорчук A. М., Третьяк С. И. Чрезкожное дренирование псевдокист поджелудочной железы под контролем УЗИ. Анналы хирур гепатол 1999; 4: 2: 145-148.
7. Гаркави Л. X., Квакина Е. Б., Уколова М. A. Адаптационные реакции и резистентность организма. Ростов-на-Дону; 1979.
8. Гланц С. Медико-биологическая статистика. М.: 1999.
Review
For citations:
Morozov S.V., Poluektov V.L., Dolgikh V.T., Reis A.B., Ershov A.V., Reis B.A. Immune Disturbances in Patients with Postnecrotic Pseudocysts of the Pancreas. Antibiot Khimioter = Antibiotics and Chemotherapy. 2012;57(11-12):22-25. (In Russ.)
Views:
293
Email this article 