Algorithm of Identification of Atypical Variants of Staphylococci, Pathogens of Chronic Pyoinflammatory Processes in Humans
Abstract
Staphylococcal pathogens of chronic relapsing infections, such as cystic pneumosclerosis and osteomyelitis are characterized by atypical morphology of the colonies (atypical variants of staphylococci) and present a subpopulation in clinically significant staphylococci. Since the loss of some phenotypic characteristics important for the genus Staphylococcus due to mutations, identification of such staphylococcal variants is difficult and sometimes impossible. An algorithm of identification of atypical variants of S.aureus (SSCVs) was developed. The advantages of the molecular methods and in particular the tRNA-PCR analysis, as well as the use of the diagnostic preparation Diastaph for correct identification of Staphylococcus atypical variants were shown.
About the Authors
L. N. Churkina
Institute of Microbiology and Virology, National Academy of Sciences of the Ukraine
Russian Federation
Russian Federation
S. I. Bidnenko
Institute of Traumatology and Orthopedics, Medical Academy of Sciences of the Ukraine
Russian Federation
Russian Federation
M. .. Vaneechoutte
Gent University
Russian Federation
Russian Federation
L. V. Avdeeva
Institute of Microbiology and Virology, National Academy of Sciences of the Ukraine
Russian Federation
Russian Federation
A. S. Makushenko
Institute of Epidemiology and Infectious Diseases, Medical Academy of Sciences of the Ukraine
Russian Federation
Russian Federation
O. B. Lutko
Institute of Traumatology and Orthopedics, Medical Academy of Sciences of the Ukraine
Russian Federation
Russian Federation
N. M. Oserjanskaja
Institute of Traumatology and Orthopedics, Medical Academy of Sciences of the Ukraine
Russian Federation
Russian Federation
N. B. Perunova
Institute of Cellular and Intracellular Symbiosis, Urals Branch of Russian Academy of Sciences
Russian Federation
Russian Federation
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Review
For citations:
Churkina L.N., Bidnenko S.I., Vaneechoutte M..., Avdeeva L.V., Makushenko A.S., Lutko O.B., Oserjanskaja N.M., Perunova N.B. Algorithm of Identification of Atypical Variants of Staphylococci, Pathogens of Chronic Pyoinflammatory Processes in Humans. Antibiot Khimioter = Antibiotics and Chemotherapy. 2013;58(11-12):26-30. (In Russ.)
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