Prevalence of Types TEM, SHV and CTX-M /3LES Among Pathogens of Chronic Pyelonephritis
Abstract
There Is lately observed an increase in the resistance of the main pathogens of urologie infection to β-lactam antibiotics due to production of plasmid-induced в-lactamases. The aim of the study was to reveal types TEM, SHV and CTX-M plasmid β-lactamases among uropathogens. Out of 115 isolates, 30 (26.1%) strains produced β-lactamases. Genes blaTEM and blaCTX-Mwere the most frequent. Most of the isolates were resistant to ampicillin (73.3%), ciprofloxacin (46.7%), levofloxacin (43.3%), gentamicin (40%). The βLES-producing strains were susceptible to meropenem (96.7%), nitroxolin (83.3%), phosphomycin (70%), amikacin (70%). The presence of the resistance genes in the uropathogens was evident of a high rate of their distribution among them by the plasmids. Detection of the plasmid-induced β-lactamases is important for the optimal choice of the antibiotic for empirical therapy.
About the Authors
A. V. Bilchenko
Kharkov Medical Academy of Postgraduate Education
Russian Federation
Russian Federation
O. I. Chub
Kharkov Medical Academy of Postgraduate Education
Russian Federation
Russian Federation
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Review
For citations:
Bilchenko A.V., Chub O.I. Prevalence of Types TEM, SHV and CTX-M /3LES Among Pathogens of Chronic Pyelonephritis. Antibiot Khimioter = Antibiotics and Chemotherapy. 2014;59(11-12):24-26. (In Russ.)
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