Influence of the Parameter «The Rate of Administration» During the Test «Abnormal Toxicity» on Quality Control of Ceftriaxonе an Antibiotic of the Cephalosporin Group
Abstract
The influence of the rate of administration was examined during the test «Abnormal toxicity» on the quality control of ceftriaxonе in a comparative experimental study on the basis of the methodologies Rus. Ph. XII and Eur. Ph. Recommendations are issued for conducting study entitled «Abnormal toxicity» for the formulations of ceftriaxonе.
About the Authors
M. V. Sharoykina
Scientific Centre for Expert Evaluation of Medicinal Products of the Ministry of Health of the Russian Federation, Moscow
Russian Federation
Russian Federation
M. S. Ryabtseva
Scientific Centre for Expert Evaluation of Medicinal Products of the Ministry of Health of the Russian Federation, Moscow
Russian Federation
Russian Federation
E. L. Kovaleva
Scientific Centre for Expert Evaluation of Medicinal Products of the Ministry of Health of the Russian Federation, Moscow
Russian Federation
Russian Federation
N. P. Neugodova
Scientific Centre for Expert Evaluation of Medicinal Products of the Ministry of Health of the Russian Federation, Moscow
Russian Federation
Russian Federation
References
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Review
For citations:
Sharoykina M.V., Ryabtseva M.S., Kovaleva E.L., Neugodova N.P. Influence of the Parameter «The Rate of Administration» During the Test «Abnormal Toxicity» on Quality Control of Ceftriaxonе an Antibiotic of the Cephalosporin Group. Antibiot Khimioter = Antibiotics and Chemotherapy. 2015;60(1-2):35-38. (In Russ.)
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