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Антибиотики и Химиотерапия

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Вторичные метаболиты морских микроорганизмов. I. Вторичные метаболиты морских актиномицетов

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Аннотация

В обзоре представлены опубликованные в период с 2007 по 2014 гг. данные по вторичным метаболитам, синтезируемым определённой группой морских микроорганизмов - морскими актиномицетами. По химической структуре описанные метаболиты относятся к разным классам соединений и проявляют различную биологическую активность. Ряд метаболитов обладает антибиотическим действием в отношении бактерий, в том числе устойчивых патогенов, а также вирусов и грибов. Многие морские актиномицеты являются продуцентами цитотоксических соединений, проявляющих противораковую активность, а также синтезируют вещества - ингибиторы различных групп ферментов.

Об авторах

Т. И. Орлова
Московский государственный университет им. М.В. Ломоносова
Россия


В. Г. Булгакова
Московский государственный университет им. М.В. Ломоносова
Россия


А. Н. Полин
Московский государственный университет им. М.В. Ломоносова
Россия


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Для цитирования:


Орлова Т.И., Булгакова В.Г., Полин А.Н. Вторичные метаболиты морских микроорганизмов. I. Вторичные метаболиты морских актиномицетов. Антибиотики и Химиотерапия. 2015;60(7-8):47-59.

For citation:


Orlova T.I., Bulgakova V.G., Polin A.N. Secondary Metabolites from Marine Microorganisms. I. Secondary Metabolites from Marine Actinomycetes. Antibiotics and Chemotherapy. 2015;60(7-8):47-59. (In Russ.)

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