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Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies

Abstract

High resistance of enterococci to the currently used antibacterials, such as tetracycline, ciprofloxacin and ampicillin was observed. Streptomycin, gentamicin and vancomycin showed the highest activity against the clinical isolates of Enterococcus spp. Streptomycin and gentamicin showed the highest activity against the intestinal enterococci. The PCR revealed the presence of the genetic determinants of resistance to aminoglycosides, glycopeptides and tetracycline in the isolates. The comparison of the results of the bacteriological and genetic tests provided detection of fecal and clinical isolates of Enterococcus spp. possessing the genes of resistance to aminoglycosides and glycopeptides, still without the finally developed significant clinical resistance to the above antibacterials.

About the Authors

M. V. Sycheva
Institute of Cellular and Intracellular Symbiosis, Ural Branch of Russian Academy of Sciences; Orenburg State Agrarian University
Russian Federation


O. L. Kartashova
Institute of Cellular and Intracellular Symbiosis, Ural Branch of Russian Academy of Sciences
Russian Federation


N. E. Shchepitova
Orenburg State Agrarian University
Russian Federation


Al. A. Safronov
Orenburg State Medical University; Municipal Clinical Hospital No. 4
Russian Federation


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Review

For citations:


Sycheva M.V., Kartashova O.L., Shchepitova N.E., Safronov A.A. Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies. Antibiot Khimioter = Antibiotics and Chemotherapy. 2016;61(7-8):27-32. (In Russ.)

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ISSN 0235-2990 (Print)