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Антибиотики и Химиотерапия

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Распространение генов mcr-типа, кодирующих устойчивость к полимиксинам, в России и мире

https://doi.org/10.37489/0235-2990-2021-66-1-2-57-64

Полный текст:

Аннотация

В 2015 году впервые был описан ген устойчивости к полимиксинам mcr-типа, локализованный на мобильном генетическом элементе. После первого описания, последовали публикации, демонстрирующие глобальное распространение генов mcr-типа и роль животноводства в этом процессе. Одновременно, на фоне распространения генов приобретённой резистентности к карбапенемным антибиотикам, растёт практическое значение  полимиксинов. Данный обзор кратко суммирует принципиальные данные, посвящённые данной проблеме.

Об авторах

В. А. Агеевец
Детский научно-клинический центр инфекционных болезней
Россия

Агеевец Владимир Андреевич — к. б. н.
Санкт-Петербург

 



И. В. Лазарева
Детский научно-клинический центр инфекционных болезней; Санкт-Петербургский государственный университет ветеринарной медицины
Россия

Лазарева Ирина Владимировна — к. м. н.

Санкт-Петербург



О. С. Сулян
Детский научно-клинический центр инфекционных болезней
Россия

Сулян Офелия Спартаковна

Санкт-Петербург



А. А. Сухинин
Санкт-Петербургский государственный университет ветеринарной медицины
Россия

Сухинин Александр Александрович

Санкт-Петербург



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Для цитирования:


Агеевец В.А., Лазарева И.В., Сулян О.С., Сухинин А.А. Распространение генов mcr-типа, кодирующих устойчивость к полимиксинам, в России и мире. Антибиотики и Химиотерапия. 2021;66(1-2):57-64. https://doi.org/10.37489/0235-2990-2021-66-1-2-57-64

For citation:


Ageevets V.A., Sulyan О.S., Lazareva I.V., Sukhinin A.A. Dissemination of MCR-Type Genes Encoding Polymyxin Resistance in Russia and Across the Globe. Antibiotics and Chemotherapy. 2021;66(1-2):57-64. (In Russ.) https://doi.org/10.37489/0235-2990-2021-66-1-2-57-64

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