Methods of Preoperative Morphological Verification of Skin Melanoma. Current Approaches and Development Prospects
I. A. Polyakov,
E. Yu. Neretin,
K. S. Titov,
N. Yu. Sokolov,
S. S. Lebedev,
V. M. Kulushev,
T. A. Yakusheva https://doi.org/10.37489/0235-2990-2026-71-1-2-42-47
EDN: QWGCGF
Abstract
Cutaneous melanoma (CM) is a serious problem of modern oncology, both in Russia and in many countries of the world. According to the Global Canсer Registry, 331,722 new cases of cutaneous melanoma were reported in 2022, of which 4% were patients from the Russian Federation. Skin melanoma accounts for 70.3% of deaths in patients with malignant skin tumors. Over the past decade, there has been an annual increase in melanoma cases by 3–4%, especially among people with light skin phototypes. Morphological verification of primary cutaneous melanoma (CM) is a critically important stage in the diagnosis and determination of adequate treatment tactics for this disease. Histological and cytological verification are necessary methods for accurate confirmation of the diagnosis and determination of prognostic factors for the disease. This review aims to analyze the diagnostic value of various methods of primary verification of CM, as well as further prospects for improving diagnostics.
About the Authors
I. A. Polyakov
Moscow Botkin Multidisciplinary Scientific-Clinical Center
Russian Federation
Competing Interests:
Russian Federation
Ilya A. Polyakov — Oncologist at the Oncology Department No. 1
Moscow
Competing Interests:
Авторы заявляют об отсутствии конфликта интересов.
E. Yu. Neretin
Moscow Botkin Multidisciplinary Scientific-Clinical Center
Russian Federation
Competing Interests:
Russian Federation
Evgeny Yu. Neretin — D. Sc. in Medicine, Oncologist, Senior Researcher
Moscow
Competing Interests:
Авторы заявляют об отсутствии конфликта интересов.
K. S. Titov
Moscow Botkin Multidisciplinary Scientific-Clinical Center
Russian Federation
Competing Interests:
Russian Federation
Konstantin S. Titov — D. Sc. in Medicine, Professor, Oncologist, Surgeon, Leading Researcher
Moscow
Competing Interests:
Авторы заявляют об отсутствии конфликта интересов.
N. Yu. Sokolov
Moscow Botkin Multidisciplinary Scientific-Clinical Center
Russian Federation
Competing Interests:
Russian Federation
Nikolay Yu. Sokolov — Ph. D. in Medicine, Oncologist, Senior Researcher
Moscow
Competing Interests:
Yu.
S. S. Lebedev
Moscow Botkin Multidisciplinary Scientific-Clinical Center; Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation
Russian Federation
Competing Interests:
Russian Federation
Sergey S. Lebedev — D. Sc. in Medicine, Oncologist, Surgeon, Deputy Chief Physician for Oncology, Leading Researcher; Professor at the Department of Surgery
Moscow
Competing Interests:
Авторы заявляют об отсутствии конфликта интересов.
V. M. Kulushev
Moscow Botkin Multidisciplinary Scientific-Clinical Center
Russian Federation
Competing Interests:
Russian Federation
Vadim M. Kulushev — Ph. D. in Medicine, Oncologist, Proctologist, Head of the Oncocoloproctology Department No. 74, Senior Researcher
Moscow
Competing Interests:
Авторы заявляют об отсутствии конфликта интересов.
T. A. Yakusheva
Moscow Botkin Multidisciplinary Scientific-Clinical Center
Russian Federation
Competing Interests:
Russian Federation
Tatyana A. Yakusheva — Oncologist, Head of the Oncology Department No. 1
Moscow
Competing Interests:
Авторы заявляют об отсутствии конфликта интересов.
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Review
For citations:
Polyakov IA, Neretin EY, Titov KS, Sokolov NY, Lebedev SS, Kulushev VM, Yakusheva TA. Methods of Preoperative Morphological Verification of Skin Melanoma. Current Approaches and Development Prospects. Antibiotiki i Khimioterapiya = Antibiotics and Chemotherapy. 2026;71(1-2):42-47. (In Russ.) https://doi.org/10.37489/0235-2990-2026-71-1-2-42-47. EDN: QWGCGF
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