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Сhronic stress as a risk factor for dyslipidemia, cardiovascular disease, and arterial hypertension: a systematic review and meta-analysis of alternative interventions

https://doi.org/10.37489/0235-2990-2025-71-1-2-77-81

EDN: JZRTRY

Abstract

Chronic psychosocial stress, dietary patterns, and physical activity levels are important modifiable factors of cardiovascular risk. Their influence is mediated through behavioral, neuroendocrine, metabolic, and psychophysiological mechanisms. The aim of this review was to systematize data on the relationship between stress, dietary patterns, physical activity, and cardiovascular risk based on a predefined literature. The analysis was based on 15 publications, including meta-analyses, systematic reviews, clinical trials, and conceptual papers on stress, hypertension, diet, cardiorespiratory fitness, mindfulness, as well as relaxation interventions. Chronic stress has been shown to be associated with a higher risk of hypertension, while social support, mindfulness-based interventions, the Mediterranean diet, soluble fiber, omega-3 fatty acids, and physical activity have been associated with a more favorable cardiometabolic profile. The integration of psychological and nutritional interventions, along with physical activity, may be considered a promising strategy for the prevention of cardiovascular disease.

About the Authors

R. Kh. Makhiev
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Rasul Kh. Makhiev — first-year resident physician, Medical Academy

Nalchik



Z. A. Kambachokova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Zareta A. Kambachokova — D. Sc. in Medicine, Professor, Department of Hospital Therapy, Medical Academy

Nalchik



M. Zh. Attaeva
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Madina Zh. Attaeva — Ph. D. in Medicine, Associate Professor, Department of Hospital Therapy, Medical Academy

Nalchik



R. Kh. Akhmatov
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Ramazan Kh. Akhmatov — 6th-year student in the General Medicine program, Medical Academy

Nalchik



S. V. Makhadzhiev
ФГБОУ ВО Кабардино-Балкарский государственный университет, им. Х. М. Бербекова
Russian Federation

Suleiman V. Makhadzhiev — 6th-year student in the General Medicine program, Medical Academy

Nalchik



L. A. Kazharova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Lyana A. Kazharova — 6th-year student in the General Medicine program, Medical Academy

Nalchik



E. S. Zhereshtieva
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Elina S. Zhereshtieva — 6th-year student in the General Medicine program, Medical Academy

Nalchik



A. M. Khazhnagoeva
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Albina M. Khazhnagoeva — 6th-year student in the General Medicine program, Medical Academy

Nalchik



D. I. Saidulkhanov
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Deni I. Saidulkhanov — 6th-year student in the General Medicine program, Medical Academy

Nalchik



B. R. Tembulatova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Birlant R. Tembulatova — 6th-year student in the General Medicine program, Medical Academy

Nalchik



M. M. Shagiriev
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Magomed M. Shagiriev — 6th-year student in the General Medicine program, Medical Academy

Nalchik



T. A. Istamulova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Tasmila A. Istamulova — 6th-year student in the General Medicine program, Medical Academy

Nalchik



A-Kh. V. Tsitsiev
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Abdul-Khamid V. Tsitsiev — 6th-year student in the General Medicine program, Medical Academy

Nalchik



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Review

For citations:


Makhiev RK, Kambachokova ZA, Attaeva MZ, Akhmatov RK, Makhadzhiev SV, Kazharova LA, Zhereshtieva ES, Khazhnagoeva AM, Saidulkhanov DI, Tembulatova BR, Shagiriev MM, Istamulova TA, Tsitsiev AV. Сhronic stress as a risk factor for dyslipidemia, cardiovascular disease, and arterial hypertension: a systematic review and meta-analysis of alternative interventions. Antibiotiki i Khimioterapiya = Antibiotics and Chemotherapy. 2026;71(1-2):77-81. (In Russ.) https://doi.org/10.37489/0235-2990-2025-71-1-2-77-81. EDN: JZRTRY

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ISSN 0235-2990 (Print)