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Diagnosis and Treatment of Stable Angina: A Modern Personalized Paradigm

https://doi.org/10.37489/0235-2990-2026-71-3-4-97-100

EDN: PAWIRV

Abstract

In modern clinical practice, stable angina is considered as part of the spectrum of chronic coronary syndromes, in which ischemic symptoms can be caused not only by epicardial atherosclerotic obstruction, but also by microvascular dysfunction or a vasospastic mechanism. The aim of this review was to systematize current data on the diagnosis and treatment of stable angina, focusing on ischemic mechanisms, the choice of instrumental methods, as well as the rationale for treatment strategies. Analysis of the available sources shows that a significant proportion of patients experience persistent anginal symptoms in the absence of hemodynamically significant stenosis, and the most informative tools for clarifying the ischemic mechanism are FFR/iFR, PET stress test, and coronary CT angiography. Optimal drug therapy remains the basis of treatment, while revascularization is indicated only when the functional significance of the lesion is proven. For refractory angina, spinal stimulation may be considered in specialized centres.

About the Authors

Z. A. Kambachokova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Zareta A. Kambachokova — D. Sc. in Medicine, Professor at the Department of Hospital Therapy, Medical Academy

Nalchik



A. M. Akhmadova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Amira M. Akhmadova — 6th-year student majoring in General Medicine

Nalchik



D. R. Dzhemakulova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Diana R. Dzhemakulova — graduate 

Nalchik



A. Z. Kashirokov
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Adam Z. Kashirokov — 6th-year student majoring in General Medicine

Nalchik



T. I. Miziev
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Temirlan I. Miziev — 6th-year student majoring in General Medicine

Nalchik



M. M. Mamikova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Amina R. Mamieva — 6th-year student majoring in General Medicine

Nalchik



A. R. Mamieva
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Maryat M. Mamikova — 6th-year student majoring in General Medicine

Nalchik



K. I. Sozaeva
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Karina I. Sozaeva — 6th-year student majoring in General Medicine

Nalchik



A. M. Sibilova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Alina M. Sibilova — 6th-year student majoring in General Medicine

Nalchik



A. A.-A. Chotchaeva
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Anisat A.-A. Chotchaeva — graduate of the Medical Academy

Nalchik



S. Kh. Etteeva
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Salima Kh. Etteeva — 6th-year student majoring in General Medicine

Nalchik



K. L. Chechenova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Karina L. Chechenova — graduate of the Medical Academy

Nalchik



A. A. Tengizova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Alina A. Tengizova — 6th-year student majoring in General Medicine

Nalchik



A. R. Edgulova
Kabardino-Balkarian State University named after H. M. Berbekov
Russian Federation

Amina R. Edgulova — 6th-year student majoring in Pediatrics at the Faculty of Medicine

Nalchik



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For citations:


Kambachokova ZA, Akhmadova AM, Dzhemakulova DR, Kashirokov AZ, Miziev TI, Mamikova MM, Mamieva AR, Sozaeva KI, Sibilova AM, Chotchaeva AA, Etteeva SK, Chechenova KL, Tengizova AA, Edgulova AR. Diagnosis and Treatment of Stable Angina: A Modern Personalized Paradigm. Antibiotiki i Khimioterapiya = Antibiotics and Chemotherapy. 2026;71(3-4):97-100. (In Russ.) https://doi.org/10.37489/0235-2990-2026-71-3-4-97-100. EDN: PAWIRV

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ISSN 0235-2990 (Print)