Features of Antimicrobial Therapy of Infective Endocarditis in the Russian Federation
Abstract
The article presents the results of a multicenter study of the etiology, antibiotic sensitivity, and pharmacoepidemiology of infective endocarditis. The purpose of this study is to analyze the current practice of prescribing antimicrobial therapy to patients with infective endocarditis in the Russian Federation. The study included patients of both sexes of all age groups with definite and possible infectious endocarditis. 406 cases of infective endocarditis were analyzed (240 in the retrospective part of the study and 166 in the prospective part). Aminoglycosides and parenteral cephalosporins of the third generation were most frequently prescribed at the beginning of antimicrobial therapy; glycopeptides, fluoroquinolones, aminopenicillins, and antistaphylococcal penicillins were prescribed less often. Glycopeptide, aminoglycoside, fluoroquinolone, and parenteral III generation cephalosporins prevailed after the change of antimicrobial therapy.
About the Authors
A. I. Danilov
Smolensk State Medical University
Russian Federation
Russian Federation
R. S. Kozlov
Smolensk State Medical University
Russian Federation
Russian Federation
S. N. Kozlov
Smolensk State Medical University
Russian Federation
Russian Federation
A. V. Dekhnich
Smolensk State Medical University
Russian Federation
Russian Federation
L. P. Zharkova
Smolensk State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Danilov A.I., Kozlov R.S., Kozlov S.N., Dekhnich A.V., Zharkova L.P. Features of Antimicrobial Therapy of Infective Endocarditis in the Russian Federation. Antibiot Khimioter = Antibiotics and Chemotherapy. 2018;63(9-10):48-52. (In Russ.)
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